Background: Hypoglycemia (HG) is a common complication among diabetic patients. Many diabetics who experience HG are admitted to hospitals and usually utilize more resources. While plenty of studies examined multiple HG risk factors, there is limited knowledge about the correlation between different risk factors of HG and their impact on utilization.
Objective: To identify key factors influencing utilization among diabetic HG patients and to examine the mechanisms and interactions between those factors.
Design: A quantitative, non-experimental, and retrospective design that is based on the selection of the study subjects from the Healthcare Cost and Utilization Project National database for the years of 2012-2014. We employed Andersen Behavioral Model of Health Services Use as the main framework for this study.
Results: Structural Equation Modeling was used as the main multivariate statistical method for the analysis. Total sample size was 4822 patients. We found that diabetes complications, renal disease, hypertension, and high Charlson comorbidity index score had the strongest impact on length of stay (LoS) as well as total charge. Geographical location of patients strongly influenced total charge. Age had an indirect impact on LoS and total charge.
Limitations: The use of secondary data seems to be the primary limitation for this study as some relevant risk factors for hypoglycemia were not available in the database.
Conclusions: This study examined the multilevel character of different factors leading to high utilization of healthcare services among HG patients admitted to hospitals. Findings of this study help clinicians and policy makers to formulate policies and protocols that aid in providing efficient care to HG patients with less utilization of resources.
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http://dx.doi.org/10.1016/j.diabres.2019.05.031 | DOI Listing |
Endocrinol Diabetes Metab
January 2025
Department of Endocrinology and Metabolism, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Objective: This study investigates the relationship between the albumin-to-creatinine ratio and diabetic retinopathy (DR) in US adults using NHANES data from 2009 to 2016. This study assesses the predictive efficacy of the urinary serum albumin-to-creatinine ratio (UACR/SACR Ratio) against traditional biomarkers such as the serum albumin-to-creatinine ratio (SACR) and urinary albumin-to-creatinine ratio (UACR) for evaluating DR risk. Additionally, the study explores the potential of these biomarkers, both individually and in combination with HbA1c, for early detection and risk stratification of DR.
View Article and Find Full Text PDFJpn J Ophthalmol
January 2025
Department of Visual Science and Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Purpose: To review hospitalized patients with Acute Retinal Necrosis (ARN) and investigate factors associated with subsequent retinal detachment (RD).
Study Design: Retrospective.
Methods: The study included 40 patients (42 eyes), categorized into non-RD (23 eyes) and RD (19 eyes) groups.
Drugs Aging
January 2025
Program for the Care and Study of the Aging Heart, Department of Medicine, Weill Cornell Medicine, 420 East 70th St, New York, NY, LH-36510063, USA.
There are several pharmacologic agents that have been touted as guideline-directed medical therapy for heart failure with preserved ejection fraction (HFpEF). However, it is important to recognize that older adults with HFpEF also contend with an increased risk for adverse effects from medications due to age-related changes in pharmacokinetics and pharmacodynamics of medications, as well as the concurrence of geriatric conditions such as polypharmacy and frailty. With this review, we discuss the underlying evidence for the benefits of various treatments in HFpEF and incorporate key considerations for older adults, a subpopulation that may be at higher risk for adverse drug events.
View Article and Find Full Text PDFCurr Cardiol Rep
January 2025
Division of Cardiology, Department of Internal Medicine II, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
Purpose Of Review: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease, characterized by hepatic steatosis with at least one cardiometabolic risk factor. Patients with MASLD are at increased risk for the occurrence of cardiovascular events. Within this review article, we aimed to provide an update on the pathophysiology of MASLD, its interplay with cardiovascular disease, and current treatment strategies.
View Article and Find Full Text PDFFam Cancer
January 2025
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Multiple endocrine neoplasia type 1 (MEN1) syndrome is an autosomal dominant disorder caused by a germline pathogenic variant in the MEN1 tumor suppressor gene. Patients with MEN1 have a high risk for primary hyperparathyroidism (PHPT) with a penetrance of nearly 100%, pituitary adenomas (PitAd) in 40% of patients, and neuroendocrine neoplasms (NEN) of the pancreas (40% of patients), duodenum, lung, and thymus. Increased MEN1-related mortality is mainly related to duodenal-pancreatic and thymic NEN.
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