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High-Dose Docosahexaenoic Acid in Newborns Born at Less Than 29 Weeks' Gestation and Behavior at Age 5 Years: Follow-Up of a Randomized Clinical Trial.
JAMA Pediatr
January 2024
SAHMRI Women and Kids, South Australian Health and Medical Research Institute, North Adelaide, South Australia, Australia.
Article Synopsis
- Children born before 29 weeks of gestation may face behavioral difficulties, potentially due to insufficient levels of DHA (docosahexaenoic acid), an important brain fatty acid.
- The study aimed to see if supplementing DHA in these infants improved their behavioral functioning by following up with parents when their children were 5 years old.
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Immunoglobulin-free strategy to prevent HBV mother-to-child transmission in Cambodia (TA-PROHM): a single-arm, multicentre, phase 4 trial.
Lancet Infect Dis
August 2022
Maternity Department, Calmette hospital, Phnom Penh, Cambodia.
Background: Prevention of mother-to-child transmission (MTCT) of hepatitis B virus (HBV) is based on administration of vaccine and immunoglobulins (HBIg) to newborns at birth and maternal antiviral prophylaxis for those with an HBV-DNA viral load of at 5·3 log IU/mL or more. Many low-income and middle-income countries face difficulty in accessing HBIg and HBV-DNA quantification. The aim of this study was to evaluate the effectiveness of an HBIg-free strategy to prevent MTCT of HBV.
View Article and Find Full Text PDFLarge outbreak of Jimsonweed (Datura stramonium) poisoning due to consumption of contaminated humanitarian relief food: Uganda, March-April 2019.
BMC Public Health
March 2022
Division of Global Health Protection, Center for Global Health, US Centers for Disease Control and Prevention, Atlanta, GA, USA.
Article Synopsis
- Jimsonweed (Datura stramonium) is a toxic plant that can cause severe gastrointestinal and neurological symptoms, leading to potential fatalities; an outbreak occurred in March 2019, affecting over 200 individuals in specific districts.
- The investigation defined suspected cases based on specific symptoms and involved a detailed retrospective cohort study to analyze dietary habits and food exposure, alongside extensive laboratory testing of food samples.
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Dietary Management of Eosinophilic Esophagitis: Tailoring the Approach.
Nutrients
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Division of Gastroenterology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56124 Pisa, Italy.
Eosinophilic esophagitis (EoE) is a unique form of non-immunoglobulin E-mediated food allergy, restricted to the esophagus, characterized by esophageal eosinophil-predominant inflammation and dysfunction. The diagnosis requires an esophago-gastroduodenoscopy with esophageal biopsies demonstrating active eosinophilic inflammation with 15 or more eosinophils/high-power field, following the exclusion of alternative causes of eosinophilia. Food allergens trigger the disease, withdairy/milk, wheat/gluten, egg, soy/legumes, and seafood the most common.
View Article and Find Full Text PDFSterility and concentration of liposomal bupivacaine single-use vial when used in a multiple-dose manner.
Vet Surg
May 2020
Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, North Carolina.
Objective: To evaluate the sterility of bupivacaine liposome injectable suspension (Nocita®) used in a multiple-dose fashion for 5 days.
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