Using acridine orange fluorochrome staining of fixed smears of peripheral blood the authors have investigated the lymphocyte functional activity in epileptic patients receiving the conventional anticonvulsive therapy including lithium carbonate. It has been established that the dynamics of the functional activity of lymphocytes in epileptic patients show no direct relationship with the therapeutic effect. Cytochemical parameters of the lymphocyte functional activity change in parallel with the clinical picture of the disease under the impact of treatment, i.e., they are directly correlated with the clinical pattern.
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