AI Article Synopsis
- A 59-year-old man was diagnosed with thymic adenocarcinoma, a rare cancer originating in the thymus, and found to have a large mediastinal mass and bone metastases.
- Despite extensive testing, no primary tumor in the gastrointestinal tract was identified, leading to the treatment with colon cancer chemotherapy regimens CapeOX and FOLFIRI/cetuximab.
- The patient unfortunately passed away six months after his diagnosis, and an autopsy confirmed the primary cancer as thymic adenocarcinoma, marking this case as the first known instance of using colon cancer treatments for this specific type of metastatic thymic cancer.
Article Abstract
We report the case of a 59-year-old man with thymic adenocarcinoma who was treated with colon cancer chemotherapy. He was referred to our hospital for an anterior mediastinal mass and multiple bone metastases that were found by computed tomography. Needle biopsy of the mediastinal tumor revealed a caudal-type homeobox 2 (CDX2)-positive adenocarcinoma. Neither upper nor lower gastrointestinal endoscopic examinations revealed any evidence of a primary tumor. The patient was administered CapeOX (capecitabine and oxaliplatin) and FOLFIRI (fluorouracil, leucovorin and irinotecan)/cetuximab. He died 6 months after diagnosis. Primary thymic adenocarcinoma was confirmed by autopsy. As far as we know, this is the first report in which colon cancer chemotherapy was used to treat CDX2-positive metastatic thymic adenocarcinoma.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498364 | PMC |
| http://dx.doi.org/10.1007/s13691-015-0239-1 | DOI Listing |
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