Ovarian Cycle Stages Modulate Alzheimer-Related Cognitive and Brain Network Alterations in Female Mice, by Lauren Broestl, Kurtresha Worden, Arturo J. Moreno, Emily J. Davis, Dan Wang, Bayardo Garay, Tanya Singh, Laure Verret, Jorge J. Palop, and Dena B. Dubal.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565846PMC
http://dx.doi.org/10.1523/ENEURO.0179-19.2019DOI Listing

Publication Analysis

Top Keywords

ovarian cycle
8
cycle stages
8
estrogen-dominant ovarian
4
stages associated
4
associated neural
4
neural network
4
network dysfunction
4
dysfunction cognitive
4
cognitive behavioral
4
behavioral deficits
4

Similar Publications

Affective, behavioral, and cognitive (i.e., personality) states fluctuate across situations and context, yet the biological mechanisms regulating them remain unclear.

View Article and Find Full Text PDF

Influence of Menstrual Phase and Symptoms on Sleep Before and After Matches for Professional Footballers.

Scand J Med Sci Sports

January 2025

School of Sport, Exercise and Rehabilitation, Faculty of Health, University of Technology Sydney, Ultimo, Australia.

This study investigated the association of menstrual cycle phase and symptoms with objective and subjective sleep measures from professional footballers before and after matches. Twenty-three non-hormonal contraceptive-using professional footballers (from four clubs) were monitored for up to four menstrual cycles during a domestic league season. Menstrual phases (menstruation, mid-late follicular, luteal) were determined using calendar counting and urinary hormone tests (luteinizing hormone and pregnandiol-3-glucuronide).

View Article and Find Full Text PDF

Background Polycystic ovary syndrome (PCOS) poses a significant health concern among reproductive-aged women and is characterized by ovarian dysfunction, hyperandrogenism, and insulin resistance. This study aims to assess the efficacy and safety of metformin and myo-inositol combination therapy compared to metformin monotherapy in patients with PCOS. Materials and methods This was a phase III, double-blind, randomized controlled clinical trial.

View Article and Find Full Text PDF

Introduction: The present scientific consensus is that the menstrual cycle (MC) and hormonal contraceptive (HC) cycle only influence performance trivially. Nevertheless, athletes perceive changes in performance that they associate with different phases of their hormonal cycle.

Methods: A total of 959 female athletes completed a questionnaire, of which 750 were included in the present analysis.

View Article and Find Full Text PDF

Drug repurposing has potential to improve outcomes for high-grade serous ovarian cancer (HGSOC). Repurposing drugs with PARP family binding activity may produce cytotoxic effects through the multiple mechanisms of PARP including DNA repair, cell-cycle regulation, and apoptosis. The aim of this study was to determine existing drugs that have PARP family binding activity and can be repurposed for treatment of HGSOC.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!