Chloropolysporins A, B and C, novel glycopeptide antibiotics from Faenia interjecta sp. nov. IV. Partially deglycosylated derivatives.

Chloropolysporins A, B and C, new members of the glycopeptide antibiotic family, were enzymatically and chemically converted to their partially deglycosylated derivatives. The alpha- and beta-avoparcins were also deglycosylated by the same method. The conversions were achieved by treatments with rhamnosidase (Naringinase) and alpha-mannosidase, and by mild acid hydrolysis.