Influence of hyper-harmonized fullerene water complex on collagen quality and skin function.

Background: Fullerene water complex establishes the optimal order and function of biomolecules in natural, biophysical way by transducing the signal through water hydrogen bonds to biomolecules.

Objectives: This paper considers the effects of the patented hyper-harmonized-hydroxylated fullerene water complex (3HFWC) on biophysical properties of the skin collagen molecules.

Method: Optomagnetic imaging spectroscopy (OMIS) has been used for the analysis of the biophysical skin properties (diamagnetic/paramagnetic) after applying three groups of different cosmetic products. Tested cosmetic products were prepared by replacing the active ingredients with 3HFWC or with water in four commercial products. The original commercial creams and their vehiculums with water added served as control groups. Data were statistically analyzed using paired t test in R software.

Results: t Test gave statistically significant results for all of the products with 3HFWC, while within the control group, only body lotion and hand cream did show statistically significant results (P < 0.05). Significant improvements in abundance and quality of collagen in the dermis were achieved with body lotion with 3HFWC (p /p ranged from 0.82 to 0.97). While body lotion vehiculum made collagen-water interaction more stable (p /p ranged from 0.3 to 0.55), hand cream with 3HFWC made it more dynamic (p /p ranged from 0.63 to 0.49). Body lotion vehiculum improved the compactness of the dermis (p /p ranged from 0.2 to 1.03), as well as commercial hand cream (p /p ranged from 0.28 to 0.85).

Conclusion: Compared to the control groups, cosmetic products with 3HFWC demonstrated positive effects on the biophysical properties of the skin. Increased paramagnetic properties are linked to more unpaired electrons, their faster movement, and, finally, better signal transduction. Thus, products with 3HFWC could enable faster regeneration of collagen and prompt skin reaction to the negative environmental influences.