Decreased uric acid levels in the acute phase of Plasmodium vivax malaria.

Rev Soc Bras Med Trop

Núcleo de Estudos em Doenças Infecciosas e Parasitárias, Hospital Universitário Júlio Muller/EBSERH, Universidade Federal de Mato Grosso, Cuiabá, MT, Brasil.

Published: May 2019

Introduction: Uric acid is one of the compounds associated with the inflammatory process in malaria. It acts as an indicator of cellular damage by activating the immune response and inflammatory process.

Methods: We measured serum concentrations of uric acid in 60 symptomatic patients before and after treatment for malarial infections caused by Plasmodium vivax.

Results: Lower serum concentrations of uric acid were found during the acute phase of P. vivax malaria compared to those in its convalescent phase (p < 0.0001).

Conclusions: Patients in the acute phase of malaria had lower uric acid levels than those in its convalescent phase.

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Source
http://dx.doi.org/10.1590/0037-8682-0412-2017DOI Listing

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