Introduction: There is a considerable controversy about approaches that preserve hearing in acoustic neuroma surgery. Transtemporal approaches have the advantage of extradural drilling and minimal cerebellar retraction. We aimed to measure the limits and exposure of extended infra/retrolabyrinthine approach using temporal bone dissection and temporal high resolution computed tomography (HRCT).
Materials And Methods: Hundred temporal bone sides (unpaired) underwent HRCT. The images were used to estimate the limits and exposure of infra/retrolabyrinthine approach. Also, 10 temporal bone sides underwent the same imaging protocol then were dissected to measure actual exposure and limits of dissection. These measures were compared with those retrieved by HRCT to find if they are appropriate to be applied in general population.
Results: Mean posterior fossa angle of vision (24.5 degrees), retrolabyrinthine (internal auditory canal) IAC (58.6%), and infralabyrinthine IAC exposures (73.2%) were documented based on data retrieved from CT scan. After temporal bone dissection, posterior fossa (p = 0.139) and infralabyrinthine exposures (p = 0.674) were not statistically different comparing with measures retrieved from CT scan; however, retrolabyrinthine exposure was overestimated (p = 0.012).
Conclusion: We found that at least 20% more of IAC length can be exposed by extension of retrolabyrinthine to infralabyrinthine dissection. Infralabyrinthine exposure can be estimated preoperatively using temporal bone CT but the same is not true for retrolabyrinthine exposure.
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http://dx.doi.org/10.1097/MAO.0000000000002260 | DOI Listing |
Am J Hematol
January 2025
Division of Oncologic Sciences, Department of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
Acute myeloid leukemia (AML) is a genetically heterogeneous disease with high rates of relapse after initial treatment. Identifying measurable residual disease (MRD) following initial therapy is essential to assess response, predict patient outcomes, and identify those in need of additional intervention. Currently, MRD analysis relies on invasive, serial bone marrow (BM) biopsies, which complicate sample availability and processing time and negatively impact patient experience.
View Article and Find Full Text PDFJ Otol
October 2024
Amsterdam UMC Location Vrije Universiteit Amsterdam, Otorhinolaryngology, De Boelelaan 1117, Amsterdam, the Netherlands.
Objective: two new cases of temporal bone squamous cell carcinoma (TBSCC) with a bilateral occurrence are presented. Furthermore, a review of the literature was performed and the yearly incidence was calculated.
Methods: A systematic review of the literature was conducted using PRISMA guidelines.
Aging Clin Exp Res
January 2025
Orthopedics Department of the First Affiliated Hospital of Chengdu Medical College, Chengdu, China.
Background: This study aims to delineate the global, regional, and national burden of malignant neoplasms of bone and articular cartilage (MNBAC) among individuals aged 65 years and older from 1990 to 2021, stratified by age, sex, and sociodemographic index (SDI).
Methods: We harnessed data from the Global Burden of Disease Study 2021 to evaluate the prevalence, incidence, mortality, and disability-adjusted life years (DALYs) associated with MNBAC among individuals aged 65 years and older across 204 countries and territories between 1990 and 2021. The socio-demographic Index (SDI) served as a metric to examine the influence of socioeconomic development on the burden of MNBAC.
Neuroradiol J
January 2025
Department of Radiology, Medical School, University of Minnesota, USA.
Background And Purpose: Inter-hypothalamic adhesions (IHAs) are parenchymal tissue bridges traversing the third ventricle, previously reported only in the pediatric population. We aim to understand the prevalence of IHA in the adult population, assess their size and location, and ultimately investigate whether IHA volumes correlate with age.
Materials And Methods: Patients who underwent routine high-resolution 3D T2WI MRI studies of the temporal bone/internal auditory canal at an otolaryngology clinic between 2008 and 2014 were consecutively selected.
J Clin Med
December 2024
Department of Otolaryngology and Head and Neck Surgery, Faculty of Medicine, University of Tokyo, Tokyo 113-8655, Japan.
Artificial Intelligence (AI) is a concept whose goal is to imitate human intellectual activity in computers. It emerged in the 1950s and has gone through three booms. We are in the third boom, and it will continue.
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