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Granuloma Annulare of the Palms in a Patient on Ribociclib for Metastatic Breast Cancer.
Cureus
November 2024
Dermatology, North Branch Dermatology, Chicago, USA.
Granuloma annulare (GA) is a benign inflammatory skin condition that most commonly presents on the dorsal surfaces of the hands and feet. The etiology of GA is unknown; however, it has been associated with multiple triggers, including malignancy and targeted cancer therapy drugs. This case report describes a 66-year-old female with metastatic breast cancer on ribociclib who presented with painful, erythematous papules on the palmar surfaces of the hands.
View Article and Find Full Text PDF[Thorns in hands, think in spiny keratoderma].
Medicina (B Aires)
October 2024
Servicio de Clínica Médica, Hospital Británico de Buenos Aires, Buenos Aires, Argentina.
Article Synopsis
- * Histological analysis shows these lesions are made up of distinct columns of abnormal keratin on a thin outer skin layer, and sporadic cases may be linked to chronic illnesses or cancers.
- * A case study describes an elderly man with liver cirrhosis and cancer who experienced a remission of skin lesions two months after a liver transplant, suggesting the condition may relate to his cancer diagnosis.
Update on Palmar Fasciitis and Polyarthritis Syndrome: A systematic review.
Joint Bone Spine
September 2024
Department of Dermatology, Peking Union Medical College Hospital, State Key Laboratory of Complex Severe and Rare Diseases, Chinese Academy of Medical Science and Peking Union Medical College, National Clinical Research Center for Dermatologic and Immunologic Diseases, Beijing, 100730, China. Electronic address:
Objectives: This systematic review aims to (1) summarize the clinical, laboratory, and imaging characteristics of Palmar Fasciitis and Polyarthritis Syndrome (PFPAS) patients and (2) evaluate the effectiveness of different treatments.
Methods: We conducted a systematic search of three electronic databases (Scopus, Embase, and PubMed) from inception to December 31, 2023. We presented demographic and clinical features, along with laboratory factors and imaging examinations of PFPAS patients.
Understanding Palmar Fasciitis and Polyarthritis Syndrome as a Rheumatologic Paraneoplastic Syndrome: A Case Report.
Cureus
May 2024
Rheumatology, Flow Rheumatology, Phoenix, USA.
Palmar fasciitis and polyarthritis syndrome (PFPAS) is an exceedingly rare rheumatologic condition characterized by fibrotic changes in the palmar fascia with joint pains. It is known to be associated with gynecological malignancy, especially ovarian adenocarcinoma, gastric cancer, pancreatic, prostate, breast, and lung cancer. We present a unique case of a 75-year-old Caucasian female with PFPAS preceding the diagnosis of ovarian cancer by eight months.
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