AI Article Synopsis
- The study analyzed prescription patterns for bipolar disorder (BD) using Korean data, focusing on clinical features and medication use.
- Results showed that over 85% of patients experienced polypharmacy, with 51.1% in simple and 34.2% in complex polypharmacy, indicating more medication complexity among younger patients with more severe symptoms.
- The findings suggest a need for careful monitoring of weight and medication practices in patients with bipolar disorder who are on multiple drugs, as they tend to be more overweight and use fewer antidepressants but more anxiolytics.
Article Abstract
Based on Korean data from the Research on Asian Psychotropic Prescription Pattern for Bipolar Disorder, this study tried to present prescription patterns in biopolar disorder (BD) and its associated clinical features. Based on the information obtained from the study with structured questions, the tendency of prescription pattern was studied and analyzed. Polypharmacy was predominant, including simple polypharmacy in 51.1% and complex polypharmacy in 34.2% of patients. Subjects associated with simple or complex polypharmacy were significantly younger, had higher inpatient settings, a larger portion of onset with manic episode, a shorter duration of untreated illness, a shorter duration of current episode, were more overweight, used less antidepressants and used more anxiolytics. These findings can suggest higher polypharmacy rate in more severe BD and highlight the necessity of monitoring the weight of subjects with polypharmacy.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6539270 | PMC |
| http://dx.doi.org/10.30773/pi.2019.02.26.4 | DOI Listing |
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