Bioactive constituents from .

J Asian Nat Prod Res

Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming 650500, China.

Published: August 2020

Two new isopimarane diterpenoids, named 1-hydroxy-7-oxoisopimara-8, 15-diene (), 11-hydroxy-7-oxoisopimara-8(14), 15-diene (), together with six known compounds (), were isolated from the medicinal plant . All isolates were assayed for their cytotoxicity and -glucosidase inhibitory activity. Results suggested compounds , possessed significant cytotoxic activity against HepG2, HL60, and Hela cell lines with IC values ranging from 0.23 to 0.35 μM, and compounds , exhibited noticeable -glucosidase inhibitory ability with IC values of 0.25 and 0.31 μM, respectively.

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http://dx.doi.org/10.1080/10286020.2019.1618279DOI Listing

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