Innate immune checkpoint CD47 has emerged as a prominent target for cancer immunotherapy and defining biomarkers predictive of response will be a crucial step towards clinical implementation. Hereto, we investigated the importance of a previously reported requisite for SLAM family member 7(SLAMF7) expression on cancer cell phagocytosis for effective CD47 antibody therapy.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512920 | PMC |
http://dx.doi.org/10.1080/23723556.2019.1600349 | DOI Listing |
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