Aim: To do a randomized prospective interventional study for comparing the effects of a single subconjunctival triamcinolone acetonide (SCTA) injection to tapering topical loteprednol in patients undergoing phacoemulsification surgery under topical anesthesia.
Methods: A total of 400 patients were randomized into 2 groups; Group A (200 patients) received 5 mg SCTA at the end of surgery and topical ketorolac tromethamine (0.5%) with ofloxacin (0.3%) combination for 3wk. Group B (200 patients) received tapering topical loteprednol etabonate (0.5%) along with ofloxacin (0.3%) and ketorolac tromethamine (0.5%) for 3wk. Outcomes evaluated were intraocular pressure (IOP), anterior chamber cells/flare and macular oedema postoperatively at 1, 6 and 12wk.
Results: Baseline parameters were almost similar in both the groups. No statistical difference was seen between the preoperative and postoperative IOP values for Group A (=0.82) and Group B (=0.61) and postoperative IOP values in between both groups (=0.14) at 1wk. Incidence of cells/flare postoperative was statistically not significant (=0.82) in both groups at all follow up visits. Postoperative macular oedema was not observed at any follow up visit.
Conclusion: SCTA appears to be an effective alternative to prolong postoperative topical steroid use.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520266 | PMC |
| http://dx.doi.org/10.18240/ijo.2019.05.11 | DOI Listing |
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