Introduction: Silicosis is still one of the the most common occupational disease in the world. The ceramic industry is one of the main sectors where silicosis patients are increasingly reported. The aim of this study was to evaluate the differences in demographic characteristics, radiological findings and pulmonary function test results of the ceramic workers with silicosis and those did not develop the disease.
Materials And Methods: A total of 626 workers, 459 with silicosis and 167 without silicosis, working in the ceramics industry those admitted to Ankara Occupational and Environmental Diseases Hospital between 2009 and 2018 were included in the study. The cases were evaluated retrospectively.
Result: The median age and duration of work of the workers with silicosis were significantly higher (p< 0.001) compared to workers without silicosis. The risk of silicosis was found to be 22.5 times higher in 50 years or older age. Working 11-20 years and more than 20 years increased the risk of silicosis by 3.1 fold and 3.9 fold respectively. Smoking more than 10 package-years was found to increase the risk of silicosis 2 fold. The workers who had worked in clay processing, sanding, glazing or smelting were found to have 5.2-fold, 3.8-fold 2.5 and 2.4 fold higher silicosis risk, respectively.
Conclusions: In this study, it has been shown that older age, longer duration of work, smoking, working in clay processing, sanding, glazing or smelting sections increase the risk of silicosis in ceramic workers.
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http://dx.doi.org/10.5578/tt.67990 | DOI Listing |
In Vivo
December 2024
College of Biology, Hunan University, Changsha, P.R. China;
Background/aim: Silicosis, the most severe type of occupational pneumoconiosis, leads to diffuse pulmonary fibrosis without specific therapy. Ferroptosis is triggered by reactive oxygen species (ROS) and Fe overload-induced lipid peroxidation, which is involved in the progression of pulmonary fibrosis. As an important coenzyme in the process of aerobic respiration, Coenzyme Q10 (CoQ10) can enhance mitochondrial function and energy supply and reduce malondialdehyde (MDA) to limit the risk of fibrosis.
View Article and Find Full Text PDFEur Respir Rev
October 2024
School of Public Health, University of the Witwatersrand, Johannesburg, South Africa
Silicotuberculosis, the combination of silicosis and pulmonary tuberculosis (TB), remains a substantial clinical and public health problem in high TB burden countries with silica-exposed workforces. The objectives of this narrative review are to propose a definition of silicotuberculosis which includes post-tuberculous lung disease, to emphasise the importance of understanding how the two diseases modify each other, and to identify as yet unanswered questions relevant to clinical practice and disease control and mitigation. The unique aetiological relationship between silica exposure and TB is now firmly established, as is the accelerated impairment and mortality imposed by TB on individuals with silicosis.
View Article and Find Full Text PDFOccup Environ Med
December 2024
School of Public Health, Division of Environmental and Occupational Health Sciences, University of Illinois Chicago, Chicago, Illinois, USA.
Introduction: Previous studies suggest respirable crystalline silica (RCS) is an important driver of resurgent pneumoconiosis among US coal miners. Although greater attention has been focused on dust exposures in underground coal miners, surface miners are also at risk of severe disease. This study explores RCS exposure in this population.
View Article and Find Full Text PDFJ Bras Pneumol
December 2024
. Divisão de Pneumologia, Instituto do Coracao - InCor - Hospital das Clinicas -HCFMUSP - Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo (SP) Brasil.
Objective: To evaluate the incidence rates of mycobacterial infections in silicosis patients with systemic autoimmune rheumatic disease (ARD).
Methods: This was a retrospective cohort of silicosis patients between January of 1999 and December of 2023. We compared the incidence of tuberculosis and nontuberculous mycobacterial disease (NTM) in patients with silicosis with and without ARD.
Respirol Case Rep
December 2024
A 71-year-old man with silicosis was treated for infection. Antimycobacterial treatment for was terminated 1 year after a negative test result for the bacteria on sputum examination. One year following the treatment, the patient developed pneumonitis.
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