Purpose: To describe the trends in the prevalence and incidence of children with psychiatric disorders, the types of medication prescribed, and the type of physician providing the prescriptions.
Method: This retrospective study linked six population-based administrative databases (2008-2015) in Alberta, Canada.
Results: The prevalence of paediatric psychiatric disorders increased from 12.6 per 100 population in 2008 to 15.0 per 100 population in 2015, while the incidence rate increased from 2.0 per 100 population to 2.2 per 100 population in the same period. The proportion of patients dispensed any psychiatric medication increased from 21.4% in 2008 to 28.2% in 2015. Over the same period, dispensations for antidepressants increased from 7.0% to 11.2% and stimulants to treat ADHD, from 11.9% to 15.9%. For antidepressants, general practitioners (GPs) wrote the highest proportion of prescriptions (44.3% in 2011-48.1% in 2015), while paediatricians wrote the lowest proportion (8.7% in 2011-11.0% in 2015) and the proportion by psychiatrists decreased from 33.4% in 2011 to 27.2% in 2015. For stimulants to treat ADHD, paediatricians were the most frequent prescribers (36.9% in 2011-39.3% in 2015) followed by GPs as the second most frequent (33.1% in 2011-33.5% in 2015), while psychiatrists were the least likely to prescribe stimulants for ADHD.
Conclusion: The increasing trend of psychiatric diagnoses and medication prescriptions in the paediatric population is evident using population-based administrative databases. The lack of safety and adverse consequences of medication use in this cohort warrants additional monitoring data.
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http://dx.doi.org/10.1007/s00127-019-01714-w | DOI Listing |
J Neurooncol
January 2025
Department of Neurosurgery, MacKay Memorial Hospital, No. 92, Sec. 2, Zhongshan N. Rd, Taipei, 10449, Taiwan.
Purpose: Advances in multidisciplinary treatment of childhood brain tumors have significantly prolonged survival and reduced treatment-related complications. This makes the accessibility of digital neurocognitive assessment an important issue in the post-pandemic era.
Methods: Twenty pediatric brain tumor patients were recruited between August 2023 and August 2024, and a total of eight standardized Cambridge Neuropsychological Test Automated Battery (CANTAB) tests targeting executive function, memory, and attention were applied on a digital system.
Environ Geochem Health
January 2025
School of Civil Engineering and Transportation, School of Architecture and Urban Planning, Guangzhou University, Guangzhou, 510006, China.
People spend about 90% of their day indoors and are at increased risk of exposure to metal elements (MEs), water-soluble ions (WSIs) and polycyclic aromatic hydrocarbons (PAHs) contained in indoor PM. Therefore, firstly this study investigated indoor PM pollution to explore the distribution characteristics of MEs, WSIs and PAHs. Secondly, the carcinogenic risk of MEs and PAH to the population was analyzed using health risk assessment models.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
January 2025
Ecology Department, Instituto de Botânica, São Paulo, SP, Brazil.
In this study, we evaluated the pollution history by metals over the twentieth century in an urban reservoir (Garças Reservoir, Metropolitan Region of São Paulo, Southeast Brazil) by the paleolimnological approach. The concentrations of eight metals (Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn) were determined in a Pb-dated sediment core (~ 100 years of information). Metal's enrichment and pollution degree were assessed using the Consensus-Based Sediment Quality Guidelines (CBSQG), enrichment factor (EF), Geoaccumulation Index (I), and Potential Ecological Risk Index (RI).
View Article and Find Full Text PDFInt Urogynecol J
January 2025
Department of Obstetrics and Gynaecology, Medical Research Center Oulu, Research Unit of Clinical Medicine, University of Oulu and Oulu University Hospital, Kajaanintie 50, BOX 5000, 90014, Oulu, Finland.
Introduction And Hypothesis: Overactive bladder (OAB) affects 11-17% of the female population. First-line treatment with lifestyle modifications and second-line therapy with medications are often limited by inadequate efficacy or pharmacological side effects. This study was aimed at assessing the effect of 100 U onabotulinumtoxin A treatment on idiopathic OAB (iOAB) as a second-line treatment.
View Article and Find Full Text PDFHealth Econ
January 2025
Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, California, USA.
Oregon Ballot Measure 110 (BM 110) reduced the penalties for non-commercial possession of a controlled substance, downgrading them from a felony or misdemeanor to a new Class E violation, punishable by a maximum $100 fine. In this paper, we investigate whether BM 110 was associated with changes in drug-related fatal traffic crashes in Oregon after its implementation in February 2021. To do so, we used Fatality Analysis Reporting System (FARS) data from 2018 to 2021 to calculate population-adjusted state-level drug-related fatal traffic crashes.
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