Studies in human immunodeficiency virus (HIV)-infected individuals suggest excess weight gain with integrase inhibitor-based antiretroviral therapy. The HIV Prevention Trials Network Study 077 evaluated changes in weight and fasting metabolic parameters in HIV-uninfected individuals randomized to cabotegravir or a placebo. No differences between arms were found for change in weight or fasting metabolic parameters overall or for subgroups.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938971 | PMC |
| http://dx.doi.org/10.1093/cid/ciz439 | DOI Listing |
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