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http://dx.doi.org/10.33963/KP.14843DOI Listing

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Article Synopsis
  • Mitral valve prolapse (MVP) is common in Western countries and usually has a good outlook, but a small group of patients, known as arrhythmic MVP (AMVP), faces higher risks of dangerous heart rhythms and sudden cardiac death.
  • Recent studies have highlighted features that indicate severe AMVP and have contributed to understanding its causes, but determining the risk level for patients is tricky, potentially leading to both overestimating and underestimating danger.
  • The review discusses the definition, prevalence, causes, and treatment of AMVP, and suggests a collaborative approach for evaluating athletes with this condition to promote safe participation in sports while maintaining an active lifestyle.
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Lymphangiogenesis in Rheumatic Heart Valve Disease: A New Factor in the Pathogenic Conundrum.

Arterioscler Thromb Vasc Biol

April 2024

The Center for Excellence in Vascular Biology, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA (A.L., L.S.A.P., E.A.).

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Article Synopsis
  • Mitral valve prolapse (MVP) is the most common valve disorder but is complex, especially concerning its association with arrhythmias (AMVP) and risks of sudden cardiac death.
  • Recent studies reveal that MVP isn't always benign and can be linked to serious ventricular arrhythmias, necessitating a deeper understanding of AMVP and its characteristics.
  • The review suggests a risk assessment strategy for managing patients with MVP by exploring mitral annular disjunction (MAD) and its implications, advocating for updated research and clinical guidelines.
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The optimal aortic cross-clamp time in minimally invasive mitral valve surgery: still a conundrum?

Eur J Cardiothorac Surg

June 2023

Department of Cardiovascular Diseases, East Carolina Heart Institute, Brody School of Medicine, East Carolina University, Greenville, NC, USA.

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Background The management of severe mitral regurgitation (MR) after transcatheter edge-to-edge repair (TEER) remains a clinical conundrum. Considering the growing volume of TEER, more outcomes data for mitral surgery in this cohort are needed. Methods and Results Symptomatic patients with persistent or recurrent severe MR after TEER evaluated between May 2014 and June 2021 were included.

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