Microorganisms were screened for their ability to degrade ochratoxin A (OTA). Among test microorganisms, Acinetobacter calcoaceticus was found to degrade OTA. The degradation of OTA by A. calcoaceticus was studied in an ethanol-minimal salts medium with an initial OTA concentration of 10 (μg/ml at 25 and 30°C. Under these conditions, A. calcoaceticus was able to degrade OTA with an initial concentration of OTA of 10 (μg/ml. The average amounts of OTA removed by A. calcoaceticus in medium with an initial OTA concentration of 10 (μg/ml were 0.1005 and 0.0636 (μg/ml/h at 25 and 30°C, respectively. Ochratoxin A was degraded significantly by A. calcoaceticus during and after the log phase of cell growth at both incubation temperatures. It is postulated that degradation of OTA by A. calcoaceticus yielded a less toxic ochratoxin α.
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