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A Rare Case of Prurigo Pigmentosa in Iranian Sibling Couple.
Clin Case Rep
January 2025
Department of Dermatology Razi Hospital, Tehran University of Medical Sciences (TUMS) Tehran Iran.
Prurigo Pigmentosa is a rare inflammatory skin disease of unknown origin, characterized by pruritic, erythematous papules on the chest, back, neck, and anterior abdomen. The eruption resolves with reticular hyperpigmentation that cosmetically affects the patient's quality of life. Previous reports highlighted the role of the Ketogenic diet in triggering the disease in young female patients, however, no study reported the occurrence of Prurigo Pigmentosa in siblings of one family, unrelated to a ketogenic diet.
View Article and Find Full Text PDFClinical predictors of disease severity in oral lichen planus.
Clin Exp Dermatol
January 2025
Institute of Dentistry, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK.
Background: The limited understanding of factors influencing the disease progression of oral lichen planus (OLP) poses challenges in delivering effective and personalised treatment for this condition, known to increase the risk of oral cancer and adversely impact patient quality of life.
Objective: This study aimed to systematically identify clinical predictors of disease severity in OLP patients.
Methods: This cross-sectional and single-site prospective study was conducted between December 2021 and February 2024 in the Departments of Oral Medicine and Oral & Maxillofacial Surgery, Aberdeen Royal Infirmary.
Critical Crossroads: The Vital Role of Timely Diagnosis in Severe Amyopathic Dermatomyositis.
Cureus
October 2024
Internal Medicine Department, Hospital Prof. Dr. Fernando Fonseca, Lisbon, PRT.
Clinically amyopathic dermatomyositis (CADM) is an uncommon subtype of dermatomyositis (DM) characterized by the typical cutaneous manifestations of DM but without clinical or enzymatic signs of muscle inflammation. We report a case of a 61-year-old woman with a four-week history of dry cough, myalgias, chills, pleuritic chest pain, and worsening shortness of breath. She also had a five-year history of inflammatory polyarthralgia.
View Article and Find Full Text PDF[Translated article] Reticular Erythematous Mucinosis as Differential Diagnosis of the Apple-Jelly Pattern on Dermoscopy: A Case Report.
Actas Dermosifiliogr
October 2024
Dermatología, Facultad de Medicina, Universidad Nacional de Colombia, Bogotá, Colombia.
Case report: Managing pemphigus foliaceus using apremilast without systemic glucocorticosteroids or immunosuppressive agents.
Front Immunol
August 2024
Department of Dermatology, Wuhan No.1 Hospital, Wuhan, China.
Article Synopsis
- Pemphigus foliaceus (PF) is a mild form of pemphigus that shares treatment options with pemphigus vulgaris, commonly involving glucocorticosteroids and immunosuppressants, which can have significant side effects.
- A case study reported a 54-year-old woman with PF who was treated successfully with apremilast instead of systemic glucocorticosteroids or immunosuppressive agents, as she had previously seen no improvement with a topical steroid.
- The patient showed improvement with apremilast, maintaining treatment for 9 months without experiencing any side effects, indicating a potential alternative for patients unable or unwilling to use traditional treatments.
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