AI Article Synopsis
- Women experience depression and anxiety disorders at twice the rate of men, potentially due to greater sensitivity to negative emotions; this study aimed to explore brain activity differences between genders during emotional tasks.
- A functional MRI study with 30 healthy participants (15 men, 15 women) showed no significant interaction effect in stimuli responses, but revealed increased activity in women's right fusiform gyrus when viewing negative images.
- These findings suggest a connection between fusiform gyrus activity and women's heightened vulnerability to anxiety disorders, providing insights for future research.
Article Abstract
Background: Women have twice the rate of depression and anxiety disorders as men. Some studies suggest that this could be caused by women's greater sensitivity to negative emotions. Few brain imaging studies have compared the brain activity of men to women during a presentation of emotional stimuli. Our objective was to investigate brain activations in men and women during an emotional task. We hypothesized that the pattern of brain activations would differ by gender and valence of the stimuli.
Methods: We conducted a functional magnetic resonance imaging study in 30 healthy participants (15 men and 15 women). Positive, negative and neutral photographs were presented to the subjects. Participants subjectively rated the valence and intensity of the stimuli.
Results: No significant gender-by-category interaction effect was observed for the intensity or valence of the stimuli. We found that, during the presentation of negative photographs, there was a higher activity in women's right fusiform gyrus compared to men's.
Conclusion: Given the involvement of the fusiform gyrus in anxiety disorders, this study yields promising findings in order to better understand women's vulnerability to anxiety disorders.
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| http://dx.doi.org/10.1159/000499977 | DOI Listing |
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