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Background: Intimate partner violence (IPV) against women has harmful effects on their psychological and physical health. However, help-seeking for IPV is significantly low among women in the Indian context. This study examines the different factors that influence help-seeking behaviour among women in India.

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Circulating amino acid signature features urea cycle alterations associated with coronary artery disease.

Sci Rep

October 2024

Division of Sports and Exercise Medicine, Department of Sport, Exercise and Health, University of Basel, Grosse Allee 6, 4052, Basel, Switzerland.

Coronary artery disease (CAD) remains a leading cause of death worldwide and imposes a substantial socioeconomic burden on healthcare. Improving risk stratification in clinical practice could help to combat this burden. As amino acids are biologically active metabolites whose involvement in CAD remains largely unknown, this study investigated associations between circulating amino acid levels and CAD phenotypes.

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  • A meningitis outbreak in Burkina Faso from January 28 to May 5, 2019, was primarily caused by Neisseria meningitidis serogroup C (NmC), with 301 suspected cases reported across 6 districts.
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[Genetic analysis of two children with developmental delay and intellectual disability].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi

July 2023

Henan Provincial Institute of Medical Genetics, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan 450003, China.

Objective: To explore the genetic etiology of two patients with developmental delay and intellectual disability.

Methods: Two children who were respectively admitted to Henan Provincial People's Hospital on August 29, 2021 and August 5, 2019 were selected as the study subjects. Clinical data were collected, and array comparative genomic hybridization (aCGH) was carried out on the children and their parents for the detection of chromosomal microduplication/microdeletions.

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Interim Safety Profile From the Feasibility Study of the BrainGate Neural Interface System.

Neurology

March 2023

From the Center for Neurotechnology and Neurorecovery (CNTR) (D.B.R., L.B., S.S.C., C.G., R.M., M.M., L.R.H.), Department of Neurology, and Department of Neurosurgery (Z.M.W.), Massachusetts General Hospital, Boston; Harvard Medical School (D.B.R., S.S.C., L.R.H.), Boston, MA; Department of Biomedical Engineering (A.B.A., R.F.K.), Case Western Reserve University, Cleveland, OH; FES Center of Excellence, Rehab. R&D Service (A.B.A., R.F.K., J.P.M., J.A.S., B.L.W.), Louis Stokes Cleveland Department of Veterans Affairs Medical Center, OH; Center for Neurorestoration and Neurotechnology (CfNN) (M.B., J.P.D., J.D.S., L.R.H.), Rehabilitation R&D Service, Department of Veterans Affairs Medical Center, Providence, RI; Legs and Walking Lab (D.C.), Shirley Ryan AbilityLab, Chicago, IL; Department of Physical Medicine and Rehabilitation (D.C.), Northwestern University Feinberg School of Medicine, Rehabilitation Institute of Chicago, IL; Department of Neuroscience (J.P.D.), Robert J. and Nancy D. Carney Institute for Brain Science (J.P.D., J.D.S., L.R.H.), School of Engineering (J.P.D., J.D.S., L.R.H.), and Department of Rehabilitation Medicine (J.A.M.), Brown University, Providence, RI; Department of Neurological Surgery (E.N.E.), Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY; European University of Cyprus (G.F.), Nicosia, Cyprus; Department of Neurosurgery (J.M.H.), Stanford University School of Medicine, CA; Wu Tsai Neurosciences Institute (J.M.H., K.V.S.), Bio-X Institute (J.M.H., K.V.S.), and Departments of Neurobiology (K.V.S.), Electrical Engineering (K.V.S.), and Bioengineering (K.V.S.), Stanford University, CA; Department of Neurological Surgery (R.F.K., J.P.M., J.A.S.), University Hospitals Case Medical Center, Cleveland, OH; Neurology Section (S.T.M.), VA Providence Health Care System, Providence, RI; Department of Neurology (S.T.M.), Alpert Medical School of Brown University, Providence, RI; Sargent Rehabilitation Center (J.A.M.), Warwick, RI; Section of Neurosurgery (R.D.P.), Department of Surgery, University of Chicago; Department of Neurosurgery (R.D.P.), Rush University Medical Center, Chicago, IL; Department of Neurology (J.S.), Barrow Neurological Institute, Phoenix, AZ; Howard Hughes Medical Institute at Stanford University (K.V.S.); Center for Neurological Restoration (B.L.W.), Cleveland Clinic, OH; and Program in Neuroscience (Z.M.W.), Harvard-MIT Program in Health Sciences and Technology, Harvard Medical School, Boston, MA.

Background And Objectives: Brain-computer interfaces (BCIs) are being developed to restore mobility, communication, and functional independence to people with paralysis. Though supported by decades of preclinical data, the safety of chronically implanted microelectrode array BCIs in humans is unknown. We report safety results from the prospective, open-label, nonrandomized BrainGate feasibility study (NCT00912041), the largest and longest-running clinical trial of an implanted BCI.

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