We present the case of a healthy young woman that was evaluated before participation in amateur sports. A systolic and diastolic murmur was heard during the physical examination. Two-dimensional echocardiography was performed, and a direct insertion of the posteromedial papillary muscle into the mitral valve leaflets was found. Mild mitral stenosis and moderate regurgitation were also found. Because she was asymptomatic, a follow-up in 6 months was planned to control the evaluation of her valve disease.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/echo.14369 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
In vivo Safety and Feasibility of a Computed Tomography-Guided Robotic Device for Percutaneous Needle Placement in Bone.
J Vasc Interv Radiol
January 2025
Gustave Roussy (GR), Département d'Anesthésie Chirurgie et Interventionnelle (DACI), Service d'Imagerie Thérapeutique, Villejuif France; Centre d'Investigation Clinique BIOTHERIS, INSERM CIC1428, Villejuif, France; Radiologie Interventionnelle, Gustave Roussy, Villejuif, France; Laboratoire de Recherche Translationnelle en Immunothérapie (LRTI), INSERM U1015, Villejuif, France; Faculté de Médecine, Paris-Saclay Université, F-94276 Le Kremlin Bicêtre, France.
Purpose: To evaluate the feasibility and accuracy of a robotic device used clinically in soft tissues (abdomen and lung), modified in design and workflow, to perform needle insertion in percutaneous bone procedures.
Methods: The primary objective was safety (severe complications) of robotic-assisted insertion in this new application. Secondary objectives were feasibility (placement technical success), performance (acceptable insertions rate), accuracy (lateral deviation), number of intermediate CT-scans and tolerance (minor/moderate complications).
Application of Gastric Tube Decompression for Rapid Tip Positioning in Bedside Blind Insertion of Nasoenteric Tubes.
J Multidiscip Healthc
January 2025
Department of Hepatobiliary Pancreatic Surgery, China-Japan Friendship Hospital, Beijing, 100029, People's Republic of China.
Objective: This study aims to examine the efficacy of gastric tube decompression in rapid tip positioning during bedside blind insertion of nasoenteric tubes.
Methods: Between August 2023 and July 2024, patients who were critically ill in the emergency intensive care unit of a tertiary hospital in Beijing who required nasoenteric tube placement were enrolled in this study. Gastric tube decompression was used to facilitate the tip positioning of nasoenteric tubes inserted blindly (without direct visualization), at the bedside.
A versatile site-directed gene trap strategy to manipulate gene activity and control gene expression in Caenorhabditis elegans.
PLoS Genet
January 2025
Department of Integrative Biology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.
The ability to manipulate gene activity and control transgene expression is essential to study gene function. While several genetic tools for modifying genes or controlling expression separately are available for Caenorhabditis elegans, there are no genetic approaches to generate mutations that simultaneously disrupt gene function and provide genetic access to the cells expressing the disrupted gene. To achieve this, we developed a versatile gene trap strategy based on cGAL, a GAL4-UAS bipartite expression system for C.
View Article and Find Full Text PDFCu(II)-Catalyzed Annulative Sulfonylimination of α-Carbonyl-γ-alkynyl Sulfoxonium Ylides through Sulfoxonium Ylide Elimination for Access to ()-1-Isochromenes.
J Org Chem
January 2025
School of Chemistry & Materials Science, Jiangsu Normal University, Xuzhou 221116, China.
1-Isochromene scaffolds are ubiquitous in natural products and significant bioactive molecules. Although several methods for these molecular syntheses have been developed, reports on the efficient construction of iminated isochromenes are still rather limited. Herein, we report a new Cu(II)-catalyzed annulation and sulfonylimination cascade of α-carbonyl-γ-alkynyl sulfoxonium ylides with sulfamides, enabling direct C-C σ-bond elimination to furnish iminated ()-1-isochromenes in 51-97% yields.
View Article and Find Full Text PDFPrevalent integration of genomic repetitive and regulatory elements and donor sequences at CRISPR-Cas9-induced breaks.
Commun Biol
January 2025
Bioscience Program, Biological and Environmental Science and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, 23955-6900, Kingdom of Saudi Arabia.
CRISPR-Cas9 genome editing has been extensively applied in both academia and clinical settings, but its genotoxic risks, including large insertions (LgIns), remain poorly studied due to methodological limitations. This study presents the first detailed report of unintended LgIns consistently induced by different Cas9 editing regimes using various types of donors across multiple gene loci. Among these insertions, retrotransposable elements (REs) and host genomic coding and regulatory sequences are prevalent.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!