Purpose: In the most recent (eighth) edition of the TNM classification, the clinical T descriptor has been adapted to measure the consolidation size of sub-solid lung cancer. Sub-centimeter non-small cell lung cancer (NSCLC) has thereby been subclassified into three groups: Tis, T1mi, and T1a; however, the revision has not been validated well. Thus, we investigated the clinicopathological characteristics and long-term oncological outcomes of sub-centimeter NSCLCs based on the solid size.
Methods: The subjects of this retrospective review were 99 patients who underwent complete resection for NSCLC with ≤ 1 cm in consolidation size on computed tomography (CT). Survival was reanalyzed after reclassification according to the new TNM classification.
Results: This cohort consisted of 14 patients with cTis tumors, 18 with cT1mi tumors, and 67 with cT1a tumors. Among the patients with tumors classified as cT1a, two had lymph node metastasis and two had vascular invasion. The cumulative incidences of recurrence at 5 and 10 years were 0% for cTis/cT1mi tumors, and 4.5% and 6.1% for cT1a tumors, respectively.
Conclusions: There may be pathological and survival differences between cTis/cT1mi tumors and cT1a tumors, but not between cTis tumors and cT1mi tumors.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00595-019-01821-w | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Iron Oxide Nanoparticle-Based T Contrast Agents for Magnetic Resonance Imaging: A Review.
Nanomaterials (Basel)
December 2024
School of Mathematics and Physics, Jiangsu University of Technology, Changzhou 213100, China.
This review highlights recent progress in utilizing iron oxide nanoparticles (IONPs) as a safer alternative to gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging (MRI). It consolidates findings from multiple studies, discussing current T contrast agents (CAs), the synthesis techniques for IONPs, the theoretical principles for designing IONP-based MRI CAs, and the key factors that impact their T contrast efficacy, such as nanoparticle size, morphology, surface modifications, valence states, and oxygen vacancies. Furthermore, we summarize current strategies to achieve IONP-based responsive CAs, including self-assembly/disassembly and distance adjustment.
View Article and Find Full Text PDFExploring the Intersection of Hegemonic Masculinity, Sexuality, and Addiction in Men: A Qualitative Study.
Healthcare (Basel)
December 2024
Department of Personality, Evaluation and Psychological Treatment, Faculty of Psychology and Speech Therapy, University of Murcia, Building 31, 30100 Murcia, Spain.
In our society, as well as in many other parts of the world, sexuality is shaped through gender-differentiated socialization. This process compels individuals to align their desires, behaviors, emotions, and thoughts with the expectations of normative sexuality, especially hegemonic heterosexuality. The primary objective of this current research was to examine the influence of hegemonic masculinity on the sexuality of men struggling with addiction.
View Article and Find Full Text PDFPurpose: In prostate and breast cancer, moderate hypofractionation (HF) has demonstrated comparable, if not greater, efficacy than conventional fractionation. There is a stark disparity in the uptake of HF between North America and Africa. Using the Consolidative Framework for Implementation Research, we evaluated barriers and facilitators for implementing HF in Sub-Saharan Africa (SSA).
View Article and Find Full Text PDFPenetrating orbital trauma: Comprehensive review and meta-analysis of bullet injuries.
Surg Neurol Int
December 2024
Department of Surgery, Baghdad Teaching Hospital, Baghdad, Iraq.
Background: Orbital bullet injuries resulting from high-velocity trauma pose significant clinical challenges due to the potential for severe ocular and systemic complications. This meta-analysis consolidates the existing body of knowledge on direct orbital bullet injuries with respect to clinical outcomes, management strategies, and long-term effects.
Methods: The literature search was conducted by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, using databases such as PubMed and Scopus.
Mapping the reporting practices in recent randomised controlled trials published in : A scoping review of methodological quality.
J Exp Orthop
January 2025
Center of Orthopaedics and Traumatology University Hospital Brandenburg/Havel, Brandenburg Medical School Theodor Fontane Brandenburg a.d.H. Germany.
Unlabelled: The official medical journals of scientific societies advocate for high-quality standards. It's important to assess whether randomized controlled trials (RCTs) in influential journals, such as the hybrid journal of the European Society of , and (), adhere to reporting guidelines and best practices. Therefore, the present scoping review aimed to explore and map the reporting practices and methodological quality in recent RCTs published in the () journal, focusing on identifying gaps in adherence to reporting guidelines and transparency.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!