Objectives: Focal spot size partially defines spatial resolution of a CT system. Many CT tubes have two focal spot sizes, with the finer one allowing more detailed imaging at the cost of photon intensity and increased heat production. Improved X-ray technology and advancement of various generations of iterative reconstruction allow the use of fine focal spot technique in CT angiography. CT neck angiography (CTNA) has been commonly performed as part of stroke imaging or in the trauma setting. This prospective study aimed to assess the efficacy of fine focal spot scanning in vessel clarity improvement, vessel calcification and arterial pulsation artefact reduction on CTNA.
Methods And Materials: Consecutive adult patients of all ages and genders who presented for CTNA were included. All CTNA were scanned with standard focal spot size (SFSS) of 1 × 1 mm in first 4 months while the CTNA in the following 4 months with fine focal spot size (FFSS) of 0.5 × 1 mm. Vessel clarity, calcification and arterial pulsation artefact of arch of aorta, brachiocephalic, subclavian, common carotid, carotid bifurcation, internal carotid, external carotid and vertebral arteries were assessed randomly using a 5-point scale by two blinded radiologists. Results were compared.
Results: There were 43 patients (mean age 60) with 97 calcified arterial segments in SFSS and 48 patients (mean age 62) with 113 calcified arterial segments in FFSS. 30 % of patients had > 50% carotid artery stenosis. No occlusion or dissection was found in the remaining arteries. Mann-Whitney test showed FFSS performed significantly better for vessel clarity (U: 48238.50, < .001,r: 0.556) and calcification artefact reduction (U: 2040.50, < .001,r: 0.564). There was no significant reduction for arterial pulsation artefact.
Conclusion: Fine focal spot technique improves vessel clarity and reduces calcification blooming artefact in CTNA. These benefits may potentially improve the assessment of arterial luminal stenosis and vessel wall pathology, including plaque morphology.
Advances In Knowledge: Beam hardening artefact from calcification particularly in the vessel wall can often reduce the clarity of vessel lumen thus affect accurate assessment of luminal stenosis. Fine focal spot technique has the advantages of reducing beam-hardening artefact of vessel wall calcifications and improving vessel wall clarity, thus it may potentially improve the assessment of arterial luminal stenosis and vessel wall pathology, including plaque morphology. It may become an important CT imaging technique in near future.
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http://dx.doi.org/10.1259/bjr.20190083 | DOI Listing |
Nat Commun
January 2025
School of Engineering Sciences, KTH Royal Institute of Technology, Applied Physics, AlbaNova, SE-106 91, Stockholm, Sweden.
Surface plasmons offer a promising avenue in the pursuit of swift and localized manipulation of magnetism for advanced magnetic storage and information processing technology. However, observing and understanding spatiotemporal interactions between surface plasmons and spins remains challenging, hindering optimal optical control of magnetism. Here, we demonstrate the spatiotemporal observation of patterned ultrafast demagnetization dynamics in permalloy mediated by propagating surface plasmon polaritons with sub-picosecond time- and sub-μm spatial- scales by employing Lorentz ultrafast electron microscopy combined with excitation through transient optical gratings.
View Article and Find Full Text PDFMol Breed
February 2025
Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, QLD 4072 Australia.
Unlabelled: Spot blotch (SB), a prevalent foliar disease of barley, is caused by the hemibiotrophic fungal pathogen . Predominately occurring in humid growing regions worldwide, SB can result in yield losses of up to 30%. Genetic resistance remains the most effective strategy for disease management; however, most Australian barley cultivars exhibit susceptibility despite the previous identification of major resistance loci.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
January 2025
College of Chemistry, Liaoning University, Shenyang 110036, China. Electronic address:
The adverse effects of Al ions on human health necessitate the development of ultra-sensitive detection methods for Al ions. In this regard, the compact and portable design of the detection substrate is of utmost importance for achieving in-situ and sensitive detection of Al ions. In our study, we have successfully developed a surface-enhanced Raman scattering (SERS) platform with gold nanoparticles (Au NPs) that was modified with histidine (His) and 4-mercaptobenzoic acid (4-MBA) for the SERS detection of Al ions.
View Article and Find Full Text PDFPLoS One
January 2025
Information Technology Section, Changshu Center for Disease Control and Prevention, Changshu, Jiangsu, China.
Objective: This study aimed to enhance the prevention and control of pulmonary tuberculosis (PTB) and provide more effective and accurate methods in Changshu City.
Methods: The PTB patients' information came from the China Information System for Disease Control and Prevention (CISDCP). The demographic data for Changshu city and towns came from the Suzhou Statistical Yearbook and the LandScan platform.
Int J Crit Illn Inj Sci
December 2024
Department of Trauma and Emergency, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India.
Background: Train collision accidents are tragic events associated with high mortality. The study aimed to comprehensively describe the clinical-epidemiological profile, disaster emergency response, and management following a train collision accident in Odisha, India.
Methods: This observational study was conducted by a tertiary care hospital in eastern India.
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