We report an uncommon presentation of bullous dermatosis by linear IgA. There are few cases reported in the literature with this form of presentation starting with mucosal lesions and then evolving into a similar bullous pemphigoid pattern. In addition, we emphasize the importance of direct immunofluorescence for the definitive diagnosis.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509886PMC
http://dx.doi.org/10.1002/ccr3.2039DOI Listing

Publication Analysis

Top Keywords

linear iga
8
bullous dermatosis
8
vancomycin-induced linear
4
iga bullous
4
dermatosis labd-an
4
labd-an atypical
4
atypical presentation
4
presentation report
4
report uncommon
4
uncommon presentation
4

Similar Publications

Background And Objectives: Gut microbial symbionts have been shown to influence the development of autoimmunity in multiple sclerosis (MS). Emerging research points to an important relationship between the microbial-IgA interface and MS pathophysiology. IgA-secreting B cells are observed in the MS brain, and shifts in gut bacteria-IgA binding have been described in some patients with MS.

View Article and Find Full Text PDF

A distinct immunophenotype in children carrying the Blautia enterotype: The Generation R study.

Clin Immunol

January 2025

Department of Immunology, Erasmus MC, University Medical Center, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands; Department of Immunology, Central Clinical School, Monash University and Alfred Hospital, Commercial Road 89, 3004 Melbourne, Victoria, Australia. Electronic address:

Objective: Studies in mouse models and human adults have shown that the intestinal microbiota composition can affect peripheral immune cells. We here examined whether the gut microbiota compositions affect B and T-cell subsets in children.

Methods: The intestinal microbiota was characterized from stool samples of 344 10-year-old children from the Generation R Study by performing 16S rRNA sequencing.

View Article and Find Full Text PDF

Heat stress greatly impairs poultry productivity, underscoring the urgent need for effective strategies to mitigate these adverse effects and improve overall poultry health. This study assessed the impact of dietary curcumin nanoparticles (CurNPs) on blood metabolites, immunity, redox status, ileal histomorphometry, and growth of broilers subjected to heat stress. A total of 400 one-day-old Ross-308 broiler chicks were randomly distributed into five groups, each consisting of eight replicates with ten birds per replicate.

View Article and Find Full Text PDF

Synergy and trade-off between plant functional traits enhance grassland multifunctionality under grazing exclusion in a semi-arid region.

J Environ Manage

January 2025

State Key Laboratory of Black Soils Conservation and Utilization, Northeast Institute of Geography and Agroecology, Chinese Academy of Sciences, Changchun, 130102, China.

Grazing exclusion is effective in restoring vegetation and ecological services in degraded grasslands within semi-arid regions. Variations in plant functional traits associated with the duration of grazing exclusion can indicate both ecological adaptability of plants and restoration processes of ecosystems. However, research on ecosystem multifunctionality (EMF) under grazing exclusion and restoration mechanisms mediated by plant functional traits is relatively limited.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!