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[Neuroleptic malignant syndrome--3 case reports].
Psychiatr Neurol Med Psychol (Leipz)
June 1990
Klinik für Neurologie und Psychiatrie, Medizinischen Akademie Carl Gustav Carus Dresden.
An account is given of three patients who exhibited a malignant neuroleptic syndrome after the administration of neuroplegics. Like other authors, we identified typical elicitation factors and clinical characteristics. In one case a catatonic dilemma with lethal issue was observed.
View Article and Find Full Text PDF[Results of long-term treatment with depot neuroleptics in schizophrenic patients].
Psychiatr Neurol Med Psychol (Leipz)
March 1988
Nervenklinik, BKH Friedrich Wolf Karl-Marx-Stadt.
An examination was instituted to determine the effectiveness of maintenance therapy involving depot neuroplegics in out-patient after-care during an average follow-up of six years. At the time of examination, 172 patients treated with Depot-Lyogen showed statistically significant lower relapse and rehospitalisation rates, a reduction of the productive schizophrenic symptoms, and improved chance of rehabilitation, compared with 55 patients without treatment. In 22% of the 270 patients on Depot-Lyogen, there were early extrapyramidal side-effects, in 4.
View Article and Find Full Text PDF[Value of neuroleptic therapy in the self assessment of schizophrenic patients].
Psychiatr Neurol Med Psychol (Leipz)
August 1987
Klinik für Frauenpsychiatrie, Bezirkskrankenhauses für Neurologie und Psychiatrie Arnsdorf bei Dresden.
On the basis of clinical self-assessment scales (von Zerssen) and the Frankfurt questionnaire of complaints, it is demonstrated by the comparison of three groups of schizophrenic patients with one control group which is not undergoing therapy with neuroplegics that within the "genuine" groups the psychopathological factors investigated recede, sometimes quite significantly. Cross-over design treatment involving the control group has not revealed any significance. We conclude that when treating schizophrenic psychoses, psychosocial measures must accompany biological measures.
View Article and Find Full Text PDF[Changes in the health state of schizophrenic patients in neuroleptic therapy].
Psychiatr Neurol Med Psychol (Leipz)
August 1986
The state of health of 135 schizophrenic patients was examined during therapy with a nigrostriatal (Haloperidol) and a mesolimbic (Clozapin) neuroplegic drug, and compared with the situation during treatment without neuroplegics. Among the methods used was the state of health scale of von Zerssen; the neuroleptic threshold was tested using Haase's handwriting test. There was evidence that the patient's health was primarily affected, but individual differential treatment with neuroplegics produced a significant improvement in this important respect.
View Article and Find Full Text PDFStarting from the consideration that communications relating to antidepressant drugs are chiefly reported by psychiatrists and that such reports deal with cases that we don't find in general practice, or at least marginally, the authors go on considering again their material consisting of 944 patients treated with antidepressants alone or associated with tranquilizers and/or with neuroplegic sedatives, hoping to gather usefull informations for a better definition of the role of these drugs in this large nosographic area. The authors could, therefore, by that way: confirm the high incidence of psychosomatic disorders among all the professional areas concerned with general practice; confirm the clear prevalence of the less symptomatic forms; verify in a high percentage of cases the coexistence of an organic disorder in way of progress or in outcome; confirm the double role of these drugs, diagnostic (ex-juvantibus) and therapeutical; suggest a third role of nosographic nature.
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