A study of the clinical analysis of blood and major metabolites of ferrokinetics in 107 breast cancer patients before treatment was conducted. In 31 (28.9%) patients revealed anemic syndrome (AS). A feature of the AS is pronounced microcytosis, erythrocyte hypochromia and low hemoglobin content in reticulocytes. Most often (n = 22; 71%) there was iron deficiency (IDA), which was characterized by a low concentration of iron (F), ferritin (FR), hepcidin 25 (GP25), interleukin-6 (IL-6) and high - soluble transferrin receptors (rTFR), transferrin (TRF). In 9 (29%) patients with AS, on the basis of a high concentration of FR, GP25, IL-6, the anemia of chronic disease (AHZ) with functional iron deficiency (FDI) was established. In 23 (74.2%) patients with AS, the was a deficiency of erythropoietin (EPO), the lowest rates were found in the group of patients with a common tumor process and FDI, with less in patients with IDA.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.18821/0869-2084-2019-64-4-210-215 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Comparative efficacy of liberal and restrictive blood transfusion strategies in anemic patients with acute myocardial infarction: A systematic review and meta-analysis of randomized controlled trials.
Transfusion
December 2024
School of Pharmacy, IMU University, Kuala Lumpur, Malaysia.
Introduction: Acute myocardial infarction (AMI) poses a significant global health burden, warranting meticulous management strategies, particularly in patients with concurrent anemia. Blood transfusion strategies play a pivotal role in optimizing oxygen delivery while minimizing transfusion-related risks. Two contrasting approaches, liberal and restrictive transfusion strategies, have emerged, yet their comparative effectiveness remains uncertain due to conflicting evidence.
View Article and Find Full Text PDFVanek jejunal tumor, a rare cause of anemic syndrome. Review of the literature.
Rev Esp Enferm Dig
December 2024
Aparato Digestivo, Hospital Clínico Universitario de Valladolid, España.
Inflammatory fibroid polyps (IPF), also called Vanek tumors, are rare, benign lesions of mesenchymal origin. They can affect both sexes with a majority incidence between 50-70 years.¹² We present the case of a 53-year-old woman with an outpatient clinic due to severe iron deficiency anemia, gastroscopy and colonoscopy without relevant findings.
View Article and Find Full Text PDFEfficacy and safety of blinatumomab for the treatment of patients relapsing after allogeneic hematopoietic cell transplantation: a systemic review and meta-analysis.
Hematology
December 2024
The Second Affiliated Hospital of Air Force Medical University, Xi'an, People's Republic of China.
Objective: We aim to evaluate the efficacy and safety of blinatumomab for the treatment of post-transplant relapse patients with acute lymphoblastic leukemia (ALL).
Methods: The search was conducted using several databases including the PubMed, Cochrane Library, Embase, Chinese National Knowledge Infrastructure (CNKI) and Wanfang Data Knowledge Service Platform to collect clinical studies related to blinatumomab. The primary outcome measures were complete remission (CR), 1-year overall survival (OS), 2-year OS, median OS and adverse events (AEs).
Prospective study of restless legs syndrome in a blood donors' sample.
Rev Clin Esp (Barc)
January 2025
Sleep and Epilepsy Unit-Clinical Neurophysiology Service, University General Hospital and Research Institute Gregorio Marañón, University Complutense of Madrid (UCM), Madrid, Spain. Electronic address:
Background And Objectives: Blood donation is suggested to increase the risk of restless legs syndrome (RLS). This study aims to assess the prevalence of RLS in Spanish blood donors and determined its potential correlation with iron metabolism parameters.
Materials And Methods: Prospective cohort study of 129 blood donors (54.
Selective Extrauterine Placental Perfusion in Monochorionic Twins Is Feasible-A Case Series.
Children (Basel)
October 2024
Division of Neonatology, Department of Pediatrics, Faculty of Medicine and University Hospital Cologne, University of Cologne, 50937 Cologne, Germany.
Article Synopsis
- Monochorionic (MC) twins face risks like twin-to-twin transfusion syndrome (TTTS) and anemia, leading to potential complications during preterm delivery.
- A study investigated a new method called selective extrauterine placental perfusion (EPP) with delayed umbilical cord clamping (DCC) for the donor twin, aiming to reduce anemia while still managing the recipient's condition.
- The results showed that using this EPP method in three cases successfully maintained healthy hemoglobin levels in the donor twins without needing blood transfusions, suggesting it could improve outcomes in similar situations.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!