AI Article Synopsis

  • * The text reports a case of a 50-year-old woman with mCRC who achieved a complete metabolic response after treatment with FOLFIRI-aflibercept, assessed via FDG PET/CT.
  • * This case highlights the potential of FDG PET/CT as an effective tool for evaluating the effectiveness of targeted therapies in mCRC.

Article Abstract

FOLFIRI-aflibercept chemotherapy is indicated in second-line treatment of metastatic colorectal cancer (mCRC) after progression under FOLFOX (±bevacizumab). Nevertheless, its proven therapeutic efficacy in clinical trials was based on partial responses. And to date, only 2 cases of complete response assessed by CT were reported in literature. We report a complete metabolic response assessed by FDG PET/CT in a 50-year-old woman with mCRC treated by FOLFIRI-aflibercept. This also confirms that FDG PET/CT is emerging as a useful approach for therapeutic assessment of targeted drugs in mCRC.

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Source
http://dx.doi.org/10.1097/RLU.0000000000002611DOI Listing

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