[Advances in m A modification and its regulation of viral replication].

Yi Chuan

Jiangsu Key Laboratory of Sericutural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.

Published: May 2019

N -methyladenosine (m A) is a prevalent modification of RNA in eukaryotes and plays an important role in the process of mRNA translocation, stabilization and translation. m A exerts different influences on the viral replication cycle, and both viral replication and host immune response to the virus are affected by m A. In this review, we summarize recent studies on the mechanism of m A modification and its effects on viral replication and host immune response, in order to provide a reference for epigenetic regulation in the viral life cycle.

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Source
http://dx.doi.org/10.16288/j.yczz.19-042DOI Listing

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