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Pericardial Abscess Due to Salmonella Typhi Infection.
Am J Trop Med Hyg
December 2024
Department of Infectious Diseases, The First Affiliated Hospital of Bengbu Medical College, Bengbu, China.
Typhoid fever is a human-specific disease caused by subspecies of Salmonella enterica (Salmonella Typhi). It spreads through ingestion of contaminated food or water and is diagnosed through blood culture or bone marrow culture. It typically presents as an intestinal infection, with a few patients developing severe disseminated infections.
View Article and Find Full Text PDFSerious infections and tuberculosis adversely impact outcomes of juvenile onset systemic lupus erythematosus in India.
Lupus
December 2024
Department of Clinical Immunology & Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Background: Infections are a major cause of morbidity and mortality in juvenile systemic lupus erythematosus (SLE). We assessed the incidence and risk factors for major infections in juvenile SLE.
Methods: A retrospective review of 225 patients of juvenile SLE (ACR 1997 criteria) with age <18 years visiting the rheumatology clinic at a single centre between 2000 to 2020 was done from case records and the hospital electronic health records.
Deep vein thrombosis and aneurysm co-occurrence: a case report and review of the literature.
J Med Case Rep
December 2024
Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran.
Article Synopsis
- A rare case report discusses a 20-year-old Iranian woman who experienced a ruptured right common iliac aneurysm one year after having deep vein thrombosis (DVT), which was treated with rivaroxaban.
- The surgical repair was successful, but she faced complications, including abdominal pain, small bowel obstruction, and a large pancreatic pseudocyst, despite ongoing anticoagulant therapy.
- The report highlights the unusual link between DVT and vascular aneurysms and emphasizes the need to consider potential complications arising from aneurysms when treating DVT in patients.
Thermal-responsive activation of engineered bacteria to trigger antitumor immunity post microwave ablation therapy.
Nat Commun
December 2024
Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou, 215123, Jiangsu, China.
Incomplete tumor removal after microwave ablation (MWA), a widely used hyperthermia-based therapy, can result in tumor recurrence. Herein, attenuated Salmonella typhimurium VNP20009 is engineered to release interleukin-15&interleukin-15-receptor-alpha (IL-15&IL-15Rα) in response to mildly elevated temperature. Such 15&15R@VNP colonizes in tumors upon intravenous injection, and the expression of IL-15&IL-15Rα is triggered by MWA.
View Article and Find Full Text PDFSalmonella typhimurium infection after lingual mucosa graft ureteroplasty: a case report and review of literature.
BMC Infect Dis
November 2024
Department of Urology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.
Article Synopsis
- Salmonella is a major foodborne pathogen linked to gastrointestinal diseases, but has not commonly been reported to cause urinary tract infections, particularly with Salmonella Typhimurium.
- A 49-year-old woman with upper ureteral stricture underwent robotic ureteroplasty, later developing a urinary infection with Salmonella typhi and E. coli, treated successfully with antibiotics.
- The case indicates that urinary tract infections may not significantly impact the survival of grafts used in surgery, suggesting effective antimicrobial therapy can keep grafts viable during recovery.
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