Partners in Crime: Neutrophil-CTC Collusion in Metastasis.

Trends Immunol

Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

Published: July 2019

A recent study in Nature (Szczerba et al. 2019;566:553-557) reports that the association of neutrophils with circulating tumor cells (CTCs) in the blood of patients with breast cancer can promote CTC proliferation and metastasis. These findings reveal a new mechanism by which the innate immune system may be co-opted to drive tumor progression.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759362PMC
http://dx.doi.org/10.1016/j.it.2019.04.009DOI Listing

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