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A new device, LMA Gastro™, on the horizon for endoscopy procedures: A narrative review.
J Anaesthesiol Clin Pharmacol
September 2024
Department of Onco-Anesthesiology and Palliative Medicine, DRBRAIRCH, AIIMS, New Delhi, India.
Interventional endoscopy procedures are challenging for anaesthesiologists due to the various patient, procedural, logistic, and position-related issues. Complex endoscopic procedures like biliary interventions and endoscopic myotomy necessitate longer procedural duration. The mode of anaesthesia is usually deep sedation without any definitive airway device and is frequently associated with hypoxemia events which can be catastrophic.
View Article and Find Full Text PDFThe Protective Role of Specialized Supraglottic Airway Devices in Gastrointestinal Endoscopy.
Anaesth Crit Care Pain Med
December 2024
Dan Benhamou. Service d'Anesthésie Réanimation Médecine Péri Opératoire. Université Paris Saclay. Hôpital Bicêtre - 78, rue du Général Leclerc. 94275 Le Kremlin Bicêtre, Cedex, France.
Inter-tissue glycan heterogeneity: site-specific glycoform analysis of mouse tissue N-glycoproteomes using MS1-based glycopeptide detection method assisted by lectin microarray.
Anal Bioanal Chem
December 2024
Molecular and Cellular Glycoproteomics Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, 305-8565, Japan.
To understand the biological and pathological functions of protein glycosylation, the glycan heterogeneities for each glycosite in a single glycoprotein need to be elucidated depending on the type and status of cells. For this aim, a reliable strategy is needed to compare site-specific glycoforms of multiple glycoprotein samples in a comprehensive manner. To analyze this "inter-heterogeneity" of samples, we previously introduced an MS1-based glycopeptide detection method, "Glyco-RIDGE.
View Article and Find Full Text PDFArthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis.
RMD Open
November 2024
Division of Rheumatology, Department of Medicine Solna, Center for Molecular Medicine, Karolinska Institutet, Solna, Sweden.
Objectives: The aim of this study was to combine deep T cell phenotyping with assessment of citrulline-reactive CD4+T cells in the pre-rheumatoid arthritis (RA) phase.
Methods: 20 anti-CCP2 positive individuals () presenting musculoskeletal complaints without clinical or ultrasound signs of synovitis; 10 arthritis progressors and 10 matched non-arthritis progressors were included. Longitudinal samples (1-3 time points) of peripheral blood mononuclear cells were assessed using HLA-class II tetramers with 12 different citrullinated candidate autoantigens combined in a >20-colour spectral flow cytometry panel.
Fasttrack intubation with the head rotated 30° following a cervical stab wound. A case report.
Int J Surg Case Rep
December 2024
Department of Anesthesia and Intensive Care, Ben Arous Trauma and Burn Center, 2013 Ben Arous, Tunisia; University of Tunis Medical School, Tunisia; University Tunis El Manar Medical School, Tunisia.
Article Synopsis
- Airway management in cervical trauma cases can be particularly difficult, especially with intubation, as it often requires maintaining a neutral head position, which may not be possible due to injury.
- A case of a 19-year-old with a blunt cervical spine injury from an assault showed he was stable but required careful positioning and intubation, which was successfully completed using a LMA Factrach.
- While traditional intubation methods may be challenging in non-standard positions, techniques like awake fiberoptic nasotracheal intubation and videolaryngoscopy are recommended for better outcomes in difficult situations.
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