AI Article Synopsis
- Recent advancements in hybrid nanogels highlight their potential as innovative drug carriers, especially those incorporating biomolecules for biomedical applications.
- The review covers critical aspects such as the physical effects of using biomolecules in hybrid nanogels, their construction, and their functionalization for better drug delivery.
- It also examines the benefits of these nanogels for controlled release, drug delivery mechanisms, and discusses the challenges and future prospects in enhancing their efficacy in targeted and real-time applications.
Article Abstract
Recently, the fast development of hybrid nanogels dedicated to various applications has been seen. In this context, nanogels incorporating biomolecules into their nanonetworks are promising innovative carriers that gain great potential in biomedical applications. Hybrid nanogels containing various types of biomolecules are exclusively designed for: improved and controlled release of drugs, targeted delivery, improvement of biocompatibility, and overcoming of immunological response and cell self-defense. This review provides recent advances in this rapidly developing field and concentrates on: (1) the key physical consequences of using hybrid nanogels and introduction of biomolecules; (2) the construction and functionalization of degradable hybrid nanogels; (3) the advantages of hybrid nanogels in controlled and targeted delivery; and (4) the analysis of the specificity of drug release mechanisms in hybrid nanogels. The limitations and future directions of hybrid nanogels in targeted specific- and real-time delivery are also discussed.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572277 | PMC |
| http://dx.doi.org/10.3390/molecules24101873 | DOI Listing |
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Article Synopsis
- Tumors are becoming more common and can be very dangerous to people's health, making accurate diagnosis really important for better treatment.
- A new type of hybrid nanogel has been created that can help doctors see tumors better in MRI scans by reacting to the heat and acidity inside tumors.
- Tests on tumors in animals showed that these nanogels work well and can help doctors find and target tumors more effectively.
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