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| http://dx.doi.org/10.1136/bmj.294.6584.1367 | DOI Listing |
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Comparison between three abbreviated methods for the diagnosis of obstructive sleep apnea syndrome in children and adolescents in a real-world setting - a prospective study using polysomnography.
Eur Arch Otorhinolaryngol
December 2024
Service d'Explorations Fonctionnelles Pédiatriques, Hôpital d'Enfants, Centre Hospitalier Universitaire de Nancy, Nancy, France.
Background: Oximetry was proposed as an abbreviated exam, easily accepted by the child, for the diagnosis of obstructive sleep apnea (OSA) for children located in regions where access to pediatric sleep labs is limited. The objective of this study was to determine the diagnostic value of the oxygen desaturation index (ODI), the number of ≥ 3% oxygen desaturations per hour of recording, obtained by portable oximetry performed in parallel with video-polysomnography (PSG), in a cohort of children, with and without comorbidities, referred for OSA.
Methods: Data from portable oximetry performed in parallel with PSG were prospectively collected.
Evaluating the added-value of video recording in respiratory polygraphy for the diagnosis of obstructive sleep apnea in children.
Sleep Med
January 2025
DevAH, Faculté de Médecine, Université de Lorraine, France; Service d'Explorations Fonctionnelles Pédiatriques, Hôpital d'Enfants, Centre Hospitalier Universitaire de Nancy, France. Electronic address:
Polysomnography (PSG) is the gold standard for diagnosing obstructive sleep apnea (OSA) in children but not always available. Abbreviated exams exist, such as respiratory polygraphy (RP), but are less accurate for OSA diagnosis. Video recording (video-RP) may provide a more precise estimation of the total sleep time (TST) compared to RP alone.
View Article and Find Full Text PDFNeurally Adjusted Ventilatory Assist to Monitor Diaphragmatic Activity in Infantile Botulism.
Pediatrics
November 2024
Department of Pediatrics, Division of Neonatal-Perinatal Medicine, Penn State Health Children's Hospital, Hershey, Pennsylvania.
Article Synopsis
- Infantile botulism is a serious neuromuscular condition that can lead to paralysis and respiratory complications, prompting the need for mechanical ventilation.
- A case study of an infant in Pennsylvania highlighted the effective use of Neurally Adjusted Ventilatory Assist (NAVA) alongside botulism immune globulin to monitor and support diaphragm function during recovery.
- The findings suggest that using a NAVA catheter is beneficial for tracking diaphragm activity, ultimately aiding in decision-making for extubation in infants recovering from infantile botulism.
Natural history and outcome of nonketotic hyperglycinemia in China.
Front Neurol
August 2024
Department of Genetics and Endocrinology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
Introduction: Nonketotic hyperglycinemia (NKH) is a rare, life-threatening genetic disorder. The patients usually show heterogeneous and nonspecific symptoms, resulting in diagnosis challenges using conventional approaches. Here, the clinical presentation and genetic features of 20 Chinese patients were examined and reported in order to clarify the natural history and prognosis of NKH in China.
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