In patients with juvenile dermatomyositis (JDM), small vessel occlusion and thrombosis result in a decrease in the capillary: muscle fiber ratio. We studied 15 patients with JDM. Six of 7 patients with clinically active JDM had elevated levels of C3d. Moreover, concentrations of fibrinopeptide A and factor VIII-related antigen were significantly increased in patients with clinically active JDM.

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http://dx.doi.org/10.1002/art.1780300513DOI Listing

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