Purpose Of Review: Myeloproliferative neoplasms (MPNs) have a high symptom burden that affects functional status, emotional well-being, and quality of life for patients. Symptom control continues to be a challenging therapeutic goal despite available pharmacologic interventions. The goal of this review is to detail recent efforts that have focused on non-pharmacologic interventions, such as wholistic or integrative medicine, as an adjunctive method to alter symptom burden in this population.
Recent Findings: We discuss the ongoing physical, nutritional, and psychological interventional efforts which represent promising non-traditional interventions to date to help reduce symptom in MPN patients. In this article, we highlight the early promising data and importance of these various non-pharmacological interventions to dampen symptom burden and reduce disease-related inflammation. Nonpharmacologic interventions represent promising therapeutic strategies to alter traditional MPN treatment paradigms and improve MPN patient care.
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http://dx.doi.org/10.1007/s11899-019-00516-w | DOI Listing |
Fam Syst Health
January 2025
School of Medicine, University of California, Riverside.
Introduction: Prolonged activation of the body's stress response from chronic exposure to adverse stressors may have a significant impact on lifelong psychosocial functioning. Screening for the impact of prolonged adversity in childhood has become an integral component of pediatric care. While past research has separately explored the impact of caregiver chronic illness and caregiver toxic stress on children, the relationship between caregiver chronic illness disability burden, caregiver parental toxic stress, and their child's psychosocial functioning is not well understood.
View Article and Find Full Text PDFCrohns Colitis 360
January 2025
Department of Social Medicine, Center for Bioethics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Background/aims: Active inflammatory bowel disease (IBD) increases the risk of pregnancy complications and contraceptive side effects, and contraceptive use may impact the clinical course of IBD. Although young people are at elevated risk for unintended pregnancy, those with IBD receive minimal disease-specific contraceptive guidance. We characterized perspectives and preferences on contraception and reproductive health counseling from young women with IBD.
View Article and Find Full Text PDFBackground: Heart failure is a condition with significant symptom burden and high hospitalization rates. Effective self-management, including recognizing symptoms and making behavior changes, is crucial but often inadequately addressed by current educational methods. To improve this, heart failure self-care vignettes were developed to measure knowledge of managing physical and psychological symptoms.
View Article and Find Full Text PDFAm J Hosp Palliat Care
January 2025
Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Context: The hospital discharge process is fraught for patients with serious illness and their caregivers.
Objectives: We sought to understand palliative care patient and caregiver concerns regarding the patient-centeredness of the hospital discharge process.
Methods: We conducted semi-structured interviews with 11 patients receiving palliative care and 4 caregivers.
Sleep Health
January 2025
The Institute for Occupational Health, Yonsei University College of Medicine, Seoul, South Korea; Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, South Korea. Electronic address:
Objectives: Long work hours and weekend work can negatively impact worker sleep; however, gender differences in these relationships have not been sufficiently studied. We explored the association between long work hours, weekend work, and insomnia symptoms, as well as the moderating effect of gender on this association.
Methods: A nationwide sample of 42,476 Korean workers (52.
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