Optimization of spray drying parameters and food additives to reduce glycation using response surface methodology in powdered infant formulas.

Food Sci Biotechnol

1Division of Food Bioscience and Technology, College of Life Science and Biotechnology, Korea University, 212 CJ Food Safety Hall, Anam-Dong, Sungbuk-gu, Seoul, 02841 Republic of Korea.

Published: June 2019

The heat-based spray drying process generating the highest level of advanced glycation end-products (AGEs) in the infant formula processing was set as a control point from which the levels of AGE markers, -carboxymethyllysine, 5-hydroxymethylfurfural, and fluorescence intensity, can be mitigated. We optimized the parameters, including inlet temperature, feeding rate, and aspirator rate during spray drying, and alternatively optimized food additives, including pyridoxine hydrochloride, dl-α-tocopheryl acetate, and l-carnitine. Using response surface methodology, the optimal condition based on our experimental condition for the inlet temperature, pump rate, and aspirator rate were 148.7 °C, 342.4 mL/h and 28.6 m/h, respectively, and the optimal conditions of pyridoxine hydrochloride, dl-α-tocopheryl acetate and l-carnitine were 0.99 mg/100 g dry mass (DM), 8 mg/100 g DM and 20.4 mg/100 g DM, respectively. These results suggest that AGEs can be mitigated by controlling the parameters and optimizing the addition of food additives during the spray-drying process.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484099PMC
http://dx.doi.org/10.1007/s10068-018-0524-9DOI Listing

Publication Analysis

Top Keywords

spray drying
12
food additives
12
response surface
8
surface methodology
8
inlet temperature
8
rate aspirator
8
aspirator rate
8
pyridoxine hydrochloride
8
hydrochloride dl-α-tocopheryl
8
dl-α-tocopheryl acetate
8

Similar Publications

Hollow Salt Prepared Through Spray Drying with Alginate Enhances Salinity Perception to Reduce Sodium Intake.

Foods

December 2024

SKL of Marine Food Processing & Safety Control, National Engineering Research Center of Seafood, Liaoning Key Laboratory of Food Nutrition and Health, School of Food Science and Technology, Dalian Polytechnic University, Dalian 116034, China.

Currently, high-salt diets have become one of the world's biggest dietary crisis and long-term high-salt diets are seriously detrimental to human health. In response to this situation, the present study proposed a saltiness enhancement strategy using alginate, which is a dietary fibre from brown algae and has many health benefits, such as regulating intestinal microbiota, anti-hypertension and anti-obesity. The comparison of alginates with different viscosities showed that alginate of 1000-1500 cps at a concentration of 1.

View Article and Find Full Text PDF

The ultrafine MoO powders were prepared by the combination of centrifugal spray drying and calcination in this work. The thermal decomposition behavior of the spherical precursor was studied. The phase constituents, morphologies, particle size, and specific surface areas of MoO powders were characterized at different temperatures.

View Article and Find Full Text PDF

The aim of this study was to compare the functional properties of linseed oil powders made of three types of wall material (OSA starch + maltodextrin, OSA starch + nutriose, and OSA starch + inulin) and two types of emulsion phases (micro- and nanoemulsion). For these independent variables, the properties of the prepared emulsions (flow curves and viscosity) and the resulting powders (encapsulation efficiency, particle size distribution, water activity, bulk and tapped density, Carr's index, color parameters, and thermal stability) were determined. The results showed that emulsion viscosity and most powder properties were affected by the emulsion type.

View Article and Find Full Text PDF

Rosehip is of notable scientific interest due to its rich content of bioactives and its wide-ranging applications in nutrition, cosmetics and pharmaceuticals. The valorization of rosehip by-products, such as pomace, is highly significant for promoting sustainability. This study investigates the development of rosehip-based powders and beverage prototypes derived from both juice and pomace to evaluate the potential use of pomace in instant beverage design and compare it with juice-based formulations.

View Article and Find Full Text PDF

CFD modelling and simulations of atomization-based processes for production of drug particles: A review.

Int J Pharm

January 2025

SSPC Research Centre, Department of Chemical Sciences & Chemical Engineering, Bernal Institute, University of Limerick, Limerick V94 T9PX Ireland. Electronic address:

Atomization-based techniques are widely used in pharmaceutical industry for production of fine drug particles due to their versatility and adaptability. Key performance measure of such techniques is their ability to provide control over critical quality attributes (CQAs) of produced drug particles. CQAs of drug particles produced via atomization critically depend on fluid dynamics of sprays; resulting mixing, heat and mass transfer; distribution of supersaturation and subsequent nucleation and growth of particles.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!