Objective: To analyze trends in mortality due to diseases and conditions fully attributable to alcohol in Brazil.
Methods: This was an ecological time-series study. Proportional, specific, and age-standardized mortality rates between 2000 and 2013 that were due to underlying or contributing causes fully attributable to alcohol use were analyzed by sex, ethnicity/skin color, age group, and region of residence in the country. Data on deaths were obtained from the Brazilian Mortality Information System (SIM). Prais-Winsten regression was used to analyze trends.
Results: Deaths with underlying causes and/or conditions contributing to death fully attributable to alcohol accounted for 2.5% of total deaths in the period. There were more deaths among men (3.8%) than among women (0.7%). In both sexes, there was a higher proportion of deaths in those 40-49 years old (27.9%) and those of black or pardo (mixed race) skin color (48.8%). Between 2000 and 2013, there was an upward trend in specific mortality rates attributable to alcohol in the country as a whole (average annual growth rate (AAGR) = 5.59%; 95% confidence interval (CI) = 3.55%-7.68%), especially in people aged less than 20 years old, in pardos (AAGR = 13.42%; 95% CI = 9.70%-17.25%), and in residents of the North region (AAGR = 17.01%; 95% CI = 14.94%-19.13%), the Northeast region (AAGR = 15.49%; 95% CI = 10.61%-20.58%), and the Midwest region (AAGR = 8.40%; 95% CI = 5.57%-11.32%).
Conclusion: Alcohol is an important and growing cause of premature death in Brazil, especially among men, black/pardo people, and the population living in the most disadvantaged regions. This overall increase in the harmful use of alcohol reflects ethnic and socioeconomic inequalities in Brazil, and it also points to the need for population-based policies to reduce the impact of morbidity and to prevent early mortality.
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http://dx.doi.org/10.26633/RPSP.2018.9 | DOI Listing |
J Community Hosp Intern Med Perspect
November 2024
HCA Healthcare, Nashville, TN 37203, USA.
Background: Alcohol abuse leads to millions of hospital admissions each year in the United States. Alcohol withdrawal syndrome (AWS) is associated with several serious complications, including seizures, delirium tremens, and death. Benzodiazepines have been the mainstay of treatment for hospitalized patients with alcohol withdrawal.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
June 2024
Department of Psychiatry, Cambridge Health Alliance, Cambridge, MA, United States.
Introduction: Rising rates of adolescent overdose deaths attributed to counterfeit prescription drugs purchased using social media have drawn national attention to how these platforms might influence substance use. Research suggests a significant relationship exists between exposure to substance-related social media content and use of drugs and alcohol, but most studies are cross-sectional and limited by recall bias. This study used an ecological momentary assessment (EMA) protocol to collect longitudinal data on social media use and online drug-related exposures associated with youth substance use.
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
College of Food Engineering, Anhui Science and Technology University, Chuzhou, 233100, PR China.
In the present study, with oregano essential oil (OEO) as the active ingredient and polyvinyl alcohol/citric acid (PVA/CA) as the composite matrix, ultraviolet (UV) responded PVA bio-active films incorporated with microcapsules, which were established by chitosan-incorporated titanium dioxide (TiO), were constructed. The UV light-triggered process changed the structure of films, including the degradation of PVA, the fracture of ester bonds and the breaking of glycosidic bonds. UV irradiation reduced the elongation at break, increased the light resistance ability, the surface hydrophobicity and the roughness, and accelerated the release of OEO in films.
View Article and Find Full Text PDFEClinicalMedicine
February 2025
Department of Breast and Thyroid Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Background: Male breast cancer (MBC) is a rare malignancy that has been under-investigated, with limited global epidemiological research dedicated to it. A comprehensive estimate of the global, regional, and national burden of MBC is valuable for policy planning. This study aims to evaluate the burden of MBC across 204 countries and territories.
View Article and Find Full Text PDFCureus
December 2024
Department of Biology, College of Education, Salahaddin University-Erbil, Erbil, IRQ.
Background: Synthesis of the original Schiff base CdCl (CHNO) compound (Schiff base complex) displays an extensive range of bioactivities and was predictably utilized to treat several syndromes.
Purpose: The goal of the existing experiment is to evaluate the gastroprotective effects of a novel Schiff base CdCl₂ (C14H21N3O2) compound in alcohol-induced gastric ulcers in rats by examining its antioxidant activity, anti-inflammatory effects, and modulation of key molecular markers, including heat shock protein-70 (HSP-70) and Bcl-2-associated X protein (Bax) proteins.
Methods: Five groups of rats were utilized in the current study.
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