Silicon Photomultipliers are potentially ideal detectors for Quantum Optics and Quantum Information studies based on mesoscopic states of light. However, their non-idealities hampered their use so far. An optimal mode of operation has been developed and it is presented here, proving that this class of sensors can actually be exploited for the characterization of both classical and quantum properties of light.
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http://dx.doi.org/10.1038/s41598-019-43742-1 | DOI Listing |
Anal Chim Acta
January 2025
Department of Power Mechanical Engineering, National Tsing Hua University, Hsinchu, Taiwan; Institute of NanoEngineering and Microsystems, National Tsing Hua University, Hsinchu, Taiwan. Electronic address:
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes joint damage and progressive destruction of adjacent cartilage and bones. Quick and accurate detection of rheumatoid factors (RF) and anti-cyclic citrullinated peptide antibodies (anti-CCP) in serum is effective in diagnosing RA and preventing its progression. However, current methods for detecting these two biomarkers are costly, time-consuming, labor-intensive, and require specialized equipment.
View Article and Find Full Text PDFJ Environ Radioact
January 2025
Canadian Hazards Information Service, Natural Resources Canada, Ottawa, Ontario, Canada.
Results from applying an advanced spatial-unfolding technique to outdoor-trial data acquired with a Silicon photomultiplier-based Compton Telescope for Safety and Security (SCoTSS) gamma imager during perimeter survey of a distributed La-140 source lying within a 500 m x 500 m exclusion zone are presented. A synthetic-data version of the experiment was also modelled using Monte Carlo simulations and reconstructed. For both experimental and synthetic data the method faithfully reproduces the shape of the activity distribution, and for synthetic data the total activity is reproduced as well.
View Article and Find Full Text PDFPhys Med Biol
January 2025
The Department of Biomedical Engineering, Huazhong University of Science and Technology, Wuhan, Hubei 430074, Wuhan, Hubei, 430074, CHINA.
Objective: In-beam positron emission tomography (PET) has important development prospects in real-time monitoring of proton therapy. However, in the beam-on operation, the high bursts of radiation events pose challenges to the performance of the PET system.
Approach: In this study, we developed a dual-head in-beam PET system for proton therapy monitoring and evaluated its performance.
Asia Ocean J Nucl Med Biol
January 2025
Department of Radiology, Faculty of Medicine, Shimane University, Izumo, Japan.
Objectives: We investigated image quality and standardized uptake values (SUVs) for different lesion sizes using clinical data generated by F-FDG-prone breast silicon photomultiplier (SiPM)-based positron emission tomography/computed tomography (PET/CT).
Methods: We evaluated the effect of point-spread function (PSF) modeling and Gaussian filtering (Gau) and determined the optimal reconstruction conditions. We compared the signal-to-noise ratio (SNR), contrast, %coefficient of variation (%CV), SUV, and Likert scale score between ordered-subset expectation maximization (OSEM) time-of-flight (TOF) and OSEM+TOF+PSF in phantom and clinical studies.
Sci Rep
December 2024
Nuclear Engineering Unit, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
This study proposes a novel, highly sensitive neutron detector design utilizing a unique multi-layered configuration. Each layer consists of a LiF: ZnS(Ag) scintillator coupled with a transparent neutron moderator that also functions as a light guide for the Silicon Photomultiplier (SiPM) light sensor. This design offers a cost-effective and readily available alternative for existing neutron detectors.
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