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| http://dx.doi.org/10.7861/clinmedicine.19-3-261b | DOI Listing |
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Triiodothyronine treatment in mice improves stroke outcome and reduces blood-brain barrier damage.
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F Langhauser, Neurology, University Hospital Essen Department of Neurology, Essen, Germany.
Objective Thyroid hormones (TH) control a variety of processes in the central nervous system and influence its response to different stimuli, such as ischemic stroke. Post-stroke administration of 3,3',5-triiodo-L-thyronine (T3) has been reported to substantially improve outcomes, but the optimal dosage and time window remain elusive. Methods Stroke was induced in mice by transient middle cerebral artery occlusion (tMCAO) and T3 was administered at different doses and time points before and after stroke.
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View Article and Find Full Text PDFSex Differences in Long COVID.
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University Hospitals Cleveland Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio.
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Antiseizure medication use in acute symptomatic seizures: A narrative review.
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Acute symptomatic seizures, occurring shortly after a central nervous system insult, constitute nearly half of all seizure cases. However, there is a conspicuous absence of clear, comprehensive, and cohesive guidelines for the management of these seizures with antiseizure medications, especially their duration of use. This lack of consensus on the optimal duration of therapy leads to prolonged treatments that may carry adverse consequences.
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