AI Article Synopsis
- Cutaneous collagenous vasculopathy is an uncommon skin condition marked by the formation of asymptomatic red blood vessel dilations (telangiectasias) and a buildup of collagen type IV around these vessels.
- A case study describes a patient with significant telangiectasias on their left arm that looked similar to another condition called unilateral nevoid telangiectasia.
- The diagnosis was supported by microscopic examinations showing thickened blood vessel walls and abnormal collagen accumulation around the vessels, as well as additional findings from transmission electron microscopy.
Article Abstract
Cutaneous collagenous vasculopathy is a rare acquired idiopathic microangiopathy characterized by progressive development of diffuse asymptomatic telangiectasias and histologically by accumulation of collagen type IV around the affected vessels. It is diagnosed by its clinical history, confirmed by light microscopy with collagen-specific immunostaining. We report a case of a patient with extensive acquired telangiectasias on the left arm, clinically resembling unilateral nevoid telangiectasia. Dilated blood vessels with thickened walls were observed in the dermis. Immunohistochemistry with collagen IV antibodies revealed marked collagen deposition around the vessels, confirming the diagnosis. Transmission electron microscopy observed duplicate and triplicate vascular basal membrane associated with deposition of amorphous material around the membranes.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486062 | PMC |
| http://dx.doi.org/10.1590/abd1806-4841.20198166 | DOI Listing |
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