Phytochemical Investigations on Chemical Constituents of (Hornem.) Hand.-Mazz. subsp. (Hornem.) Hand.-Mazz.

Iran J Pharm Res

Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, , Istanbul, Turkey.

Published: January 2019

AI Article Synopsis

  • A study on the medicinal plants of the genus Wigg. focused on the aerial parts of a specific subspecies, revealing two coumarins, three flavonoids, and six phenolic acids.
  • The chemical structures of these compounds were confirmed using various analytical methods, including UV spectroscopy and NMR.
  • Notably, this research marks the first time these compounds have been identified in this plant species and the first isolation of gossypetin from the genus Wigg.

Article Abstract

Plants of the genus Wigg., have long been used as medicinal herbs. A phytochemical investigation of the aerial parts of (Hornem.) Hand.-Mazz. subsp. (Hornem.) Hand.-Mazz. (Asteraceae) yielded two coumarins [esculetin (1), cichoriin (2)], three flavonoids [ luteolin (3), luteolin 7-O-β-D-glucoside (4), gossypetin (5)] and six phenolic acids and their derivatives [ p-coumaric acid (6), caffeic acid (7), ferulic acid (8), chlorogenic acid methyl ester (9), 3,5-di-O-caffeoylquinic acid (10), 3,5-di-O-caffeoylquinic acid methyl ester (11)]. Their structures were established conclusively by UV, ESI-MS, 1-D and 2-D NMR spectra analyses and comparison with literature data. The presence of these compounds has been shown for the first time from this species. This is the first report of the isolation of compound 5 from the genus .

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487403PMC

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Phytochemical Investigations on Chemical Constituents of (Hornem.) Hand.-Mazz. subsp. (Hornem.) Hand.-Mazz.

Iran J Pharm Res

January 2019

Department of Pharmacognosy, Faculty of Pharmacy, Istanbul University, , Istanbul, Turkey.

Article Synopsis
  • A study on the medicinal plants of the genus Wigg. focused on the aerial parts of a specific subspecies, revealing two coumarins, three flavonoids, and six phenolic acids.
  • The chemical structures of these compounds were confirmed using various analytical methods, including UV spectroscopy and NMR.
  • Notably, this research marks the first time these compounds have been identified in this plant species and the first isolation of gossypetin from the genus Wigg.
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