Objective: To evaluate the effectiveness of inverted internal limiting membrane flap in large idiopathic macular holes.
Methods: Twelve patients diagnosed with idiopathic macular holes larger than 400um underwent 23 gauge Pars Plana Vitrectomy (PPV) with inverted internal limiting flap and gas tamponade at Al-Ehsan Eye Welfare Eye Hospital, Lahore from February 2017 to February 2018. All cases were diagnosed on Spectral Domain Optical Coherence Tomography (SD-OCT) and were followed up for 6 months. At every follow-up, best corrected visual acuity and SD-OCT was done.
Results: We achieved macular hole closure in 91.6% (11/12) patients with idiopathic macular holes larger than 400um. Five out of 12 patients underwent combined phacoemulsification and PPV. One patient has flat hole closure which was considered failure. One patient was excluded from the study due to per-operative flap loss. This patient was not included in final data analysis of 12 patients. There was statistically significant gain in best corrected visual acuity after successful macular hole closure. We did not report any untoward events during or in the post-operative period.
Conclusion: Inverted internal limiting flap is an effective method for repairing large macular holes.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500808 | PMC |
http://dx.doi.org/10.12669/pjms.35.2.689 | DOI Listing |
Int Ophthalmol
January 2025
Department of Ophthalmology, Central Theater General Hospital, 627 Wuluo Road, Wuhan, 430070, China.
Purpose: The purpose is to evaluate the effect of drainage from intentional extramacular holes after internal limiting membrane insertion to treat macular hole retinal detachment (MHRD) in highly myopic eyes.
Methods: This study is a retrospective, observational, and comparative case series that included 25 consecutive highly myopic eyes with MHRD. All eyes underwent standard 23-gauge vitrectomy, inverted internal limiting membrane insertion into the macular hole, subretinal fluid drainage from an intentionally created extramacular retinal hole, and tamponade with either silicone oil (SO group, n = 13) or perfluoropropane (CF group, n = 12).
Zhonghua Yi Xue Za Zhi
January 2025
Otology Medical Center, the First People's Hospital of Foshan, Foshan528000, China.
This study aimed to investigate the efficacy of inverted door flap (IDF) combined with transcanal approach to the tympanic antrum (TCAA) technique under the endoscope for treatment of middle ear cholesteatoma. Outcomes of patients treated with combined techniques at the First People's Hospital of Foshan City between March 2021 and March 2023 were evaluated. A total of 31 patients (33 ears, 16 males and 15 females) aged (42.
View Article and Find Full Text PDFViruses
January 2025
Biological Sciences Department, University of Pittsburgh, Pittsburgh, PA 15260, USA.
Six novel phages belonging to the family were isolated using as a host. Phages MuffinTheCat, Badulia, DesireeRose, Bee17, SCoupsA, and LuzDeMundo were purified from environmental samples by students participating in the Science Education Alliance Phage Hunters Advancing Genomics and Evolutionary Science (SEA-PHAGES) program at Alliance University, New York. The phages have linear dsDNA genomes 15,438-15,636 bp with 112-120 bp inverted terminal repeats.
View Article and Find Full Text PDFSci Rep
January 2025
Exploration and Development Research Institute, PetroChina Tarim Oilfield Company, Korla, 841000, China.
The target reservoir is a typical blocky bottom water reservoir. There are several interlayers of varying scales inside it, which impact the characteristics of the oil production and water breakthrough curves of the wells in the water flooding development oilfield, resulting in strong heterogeneity within the reservoir. The Sangtamu Oilfield has an average well spacing of approximately 600 m, causing a challenge in accurately identifying the range of small-scale interlayer spreading.
View Article and Find Full Text PDFInt Ophthalmol
January 2025
Department of Ophthalmology, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang Str., Ward 11, District 5, Ho Chi Minh City, 700000, Vietnam.
Purpose: This study evaluates the effectiveness of the inverted internal limiting membrane (ILM) flap technique during vitrectomy for treating macular hole-induced retinal detachment (MHRD) in high myopia patients, a challenging complication for vitreoretinal surgeons due to its treatment complexity.
Methods: We conducted a prospective study analyzing 92 eyes diagnosed with MHRD, all undergoing vitrectomy using the inverted ILM flap technique between February 2022 and September 2024. Successful surgery was defined as achieving retinal reattachment, macular hole closure, and improvement in visual acuity by the 12-month postoperative follow-up.
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