Twenty-two diterpenoids (), including two new ones (, a tigliane-type diterpenoid and , an abietane-type diterpenoid) were isolated from the roots of Steud. Among them, compounds , , , , are isolated from this plant for the first time. Their structures were elucidated through extensive 1D, 2D NMR and the HRESIMS data. The C data of is hereby presented for the first time. The macrocyclic diterpenes and showed marked enhancement of lysosomal biosynthesis after evaluation using lysoTracker staining method.

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http://dx.doi.org/10.1080/14786419.2019.1607331DOI Listing

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