trying...
31080930202010012468-0249452019MayKidney international reportsKidney Int RepPregnancy in a Kidney Transplant Woman Under Treatment With Eculizumab for Atypical Hemolytic Uremic Syndrome: Is It Safe?733739733-73910.1016/j.ekir.2018.12.014DuvalAnnaADepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.OlagneJérômeJDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.Department of Pathology, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.CognardNoëlleNDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.Gautier VargasGabrielaGDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.JolyMélanieMDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.PerrinPeggyPDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.FritzGabrielleGDepartment of Obstetrics and Gynecology, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.FourtageMarionMDepartment of Pharmacy, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.MoulinBrunoBDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.Inserm UMR S1109, LabEx Transplantex, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.CaillardSophieSDepartment of Nephrology and Transplantation, Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.Inserm UMR S1109, LabEx Transplantex, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg University Hospital, University of Strasbourg, Strasbourg, France.engCase Reports20190115United StatesKidney Int Rep1016847522468-02492019514602019514602019514612019115epublish31080930PMC650669910.1016/j.ekir.2018.12.014S2468-0249(19)30005-1Legendre C.M., Licht C., Muus P. Terminal complement inhibitor eculizumab in atypical hemolytic–uremic syndrome. N Engl J Med. 2013;368:2169–2181.23738544Kelly R.J., Höchsmann B., Szer J. Eculizumab in pregnant patients with paroxysmal nocturnal hemoglobinuria. N Engl J Med. 2015;373:1032–1039.26352814Ardissino G., Wally Ossola M., Baffero G.M. Eculizumab for atypical hemolytic uremic syndrome in pregnancy. Obstet Gynecol. 2013;122:487–489.23884270Demir E., Yazici H., Ozluk Y. Pregnant woman with atypical hemolytic uremic syndrome delivered a healthy newborn under eculizumab treatment. Nephrol Dial Transplant. 2016;6:143–148.PMC521624428101502Andries G., Karass M., Yandrapalli S. Atypical hemolytic uremic syndrome in first trimester pregnancy successfully treated with eculizumab. Exp Hematol Oncol. 2017;6:4.PMC523717728101432Servais A., Devillard N., Frémeaux-Bacchi V. Atypical haemolytic uraemic syndrome and pregnancy: outcome with ongoing eculizumab. Nephrol Dial Transplant. 2016;31:2122–2130.27587606Huerta A., Arjona E., Portoles J. A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome. Kidney Int. 2018;93:450–459.28911789Gatault P., Brachet G., Ternant D. Therapeutic drug monitoring of eculizumab: rational for an individualized dosing schedule. MAbs. 2015;7:1205–1212.PMC496648426337866Hallstensen R.F., Bergseth G., Foss S. Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. Immunobiology. 2015;220:452–459.25468724trying2...