Hydrogen sulphide (HS) is one of the most toxic natural gas and represents a not rare cause of fatal events in workplaces. We report here a serious accidental poisoning by hydrogen sulphide inhalation involving six sailors. Three of them died while the other three survived and were transported to the emergency room. No greenish discolouration of the body, that could be a feature of these type of deaths, was observed at autopsy. Given that blood and/or urine HS detection does not allow to discriminate if it is related to inhalation or to putrefactive processes, the determination of thiosulphate, HS main metabolite, is decisive. The succession of fatal events reported here can be rebuilt by toxicological data interpretation: the subject 1 died after a longer interval of time as demonstrated by the highest blood and urine thiosulfate concentrations; the subject 2 died after a short interval of time as showed by a lower blood and urine thiosulfate concentrations than subject 1; the subject 3 died almost immediately after HS inhalation since he showed the lowest blood thiosulfate concentration, and no trace of sulphide and thiosulfate was found in the urine.
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http://dx.doi.org/10.1016/j.forsciint.2019.04.026 | DOI Listing |
Amino Acids
January 2025
Institute of Brain Science, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, 230022, P. R. China.
Metabolomics provide a promising tool for understanding dementia pathogenesis and identifying novel biomarkers. This study aimed to identify amino acid biomarkers for Alzheimer's Disease (AD) and Vascular Dementia (VD). By amino acid metabolomics, the concentrations of amino acids were determined in the serum of AD and VD patients as well as age-matched healthy controls.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Evolutionary Neuroethology, Max Planck Institute for Chemical Ecology, Jena, Germany.
The ability to tolerate otherwise toxic compounds can open up unique niches in nature. Among drosophilid flies, few examples of such adaptations are known and those which are known are typically from highly host-specific species. Here we show that the human commensal species Drosophila busckii uses dimethyldisulfide (DMDS) as a key mediator in its host selection.
View Article and Find Full Text PDFMar Pollut Bull
January 2025
Facultad de Pesquería, Universidad Nacional Agraria La Molina, Av. La Molina S/N, La Molina, Lima 15024, Peru.
Paracas Bay, located in the Humboldt Current system, is a highly variable coastal environment where hypoxia (dissolved oxygen concentrations <2 mg L) has been reported as a persistent feature of bottom conditions. In addition to hypoxia, milky water events have been reported in the bay, most likely associated with the presence of sulfides (i.e.
View Article and Find Full Text PDFFood Chem
January 2025
Departamento de Horticultura, Facultad de Ciencias Agrarias, Universidad de Talca, 2 Norte 685, Talca, Chile.
Hydrogen sulfide (HS), methanethiol (MeSH) and ethanethiol (EtSH) are volatile sulfur compounds (VSCs) produced during winemaking and are associated with negative 'reductive' aromas in wine. Anecdotal evidence suggests that oenological tannins may be used to remediate the 'reductive' character of wines, yet little scientific evidence or explanation supporting this observation has been published. In this study, it was found that the addition of oenological tannins significantly decreased HS, MeSH, and EtSH in model wine by up to 92 %, 90 % and 86 %, respectively, after two weeks of storage.
View Article and Find Full Text PDFBiochem Biophys Res Commun
January 2025
Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Química Inorgánica, Analítica y Química Física, Buenos Aires, Argentina; CONICET-Universidad de Buenos Aires, Instituto de Química Física de los Materiales, Medio Ambiente y Energía (INQUIMAE), Buenos Aires, Argentina. Electronic address:
The interest in chemical interactions between inorganic sulfur species and heme compounds has grown significantly in recent years due to their physiological relevance. The model system ferric N-acetyl microperoxidase 11 (NAcMP11Fe) enables the exploration of the mechanistic aspects of the interaction between the ferric heme group and binding sulfur ligands, without the constraints imposed by a protein matrix and the stabilizing effects of distal amino acids. In this study, we investigated the coordination of disulfane (HSSH) and its conjugate base hydrodisulfide (HSS) to NAcMP11Fe.
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