Identifying robust markers for predicting the onset of psychosis has been a key challenge for early detection research. Persecutory delusions are core symptoms of psychosis, and social cognition is particularly impaired in first-episode psychosis patients and individuals at risk for developing psychosis. Here, we propose new avenues for translation provided by hierarchical Bayesian models of behaviour and neuroimaging data applied in the context of social learning to target persecutory delusions. As it comprises a mechanistic model embedded in neurophysiology, the findings of this approach may shed light onto inference and neurobiological causes of transition to psychosis.
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| http://dx.doi.org/10.1038/s41380-019-0427-z | DOI Listing |
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Article Synopsis
- Othello syndrome is a type of psychosis where individuals wrongly believe their partner is cheating, often tied to psychiatric or neurological issues, including strokes.
- A case study details a 50-year-old woman with no prior psychiatric history who developed these delusions after a bi-thalamic stroke, resulting in severe aggressive behavior.
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