The purpose of this study was to compare internal and external load measures during two regimens (6 x 3' and 3 x 6') of a 5 vs. 5 format of play. Moreover, within-regimen changes (between sets) were also tested. Ten amateur soccer players (age: 19.8 ± 1.6 years; experience: 8.3 ± 2.1 years; height: 177.4 ± 3.8 cm; weight: 71.7 ± 4.2 kg) participated in the experiment. Internal load was measured using the CR-10 scale as the rated of perceived exertion (RPE) scale and a heart rate (HR) monitor. The measurements of total (TD), running (RD) and sprinting (SD) distances were also collected using a 10-Hz validated and reliable GPS. Comparisons between regimens revealed that the 3 x 6' regimen was significantly more intense in terms of RPE than the 6 x 3' regimen (p = 0.028; d = 0.351), although no significant differences were found in HR. Significantly greater averages of TD (p = 0.000; d = 0.871) and RD (p = 0.004; d = 0.491) were found in the 6 x 3' regimen. In both regimens, the RPE was significantly lower during the first set than in the remaining sets. On the other hand, the TD was significantly shorter in the last sets than in the earlier. In summary, the present study suggests that shorter sets may be beneficial for maintaining higher internal and external load intensities during 5 vs. 5 formats, and that a drop-in performance may occur throughout the sets in both regimens.
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http://dx.doi.org/10.3390/sports7050107 | DOI Listing |
World J Urol
January 2025
Department of Urology, Renmin Hospital of Wuhan University, 99 Zhang Zhi-dong Road, Wuhan, Hubei, 430060, P.R. China.
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ACS Nano
January 2025
College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Road, Hangzhou, Zhejiang 310058, P. R. China.
Immunocompromised populations, including cancer patients, elderly individuals, and those with chronic diseases, are the primary targets of superbugs. Traditional vaccines are less effective due to insufficient or impaired immune cells. Inspired by the "vanguard" effect of neutrophils (NE) during natural infection, this project leverages the ability of NE to initiate the NETosis program to recruit monocytes and DC cells, designing vaccines that can rapidly recruit immune cells and enhance the immune response.
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January 2025
Department of Radiology, University Medical Center Groningen, Groningen, the Netherlands.
Purpose To validate a deep learning (DL) model for predicting the risk of prostate cancer (PCa) progression based on MRI and clinical parameters and compare it with established models. Materials and Methods This retrospective study included 1607 MRI scans of 1143 male patients (median age, 64 years; IQR, 59-68 years) undergoing MRI for suspicion of clinically significant PCa (csPCa) (International Society of Urological Pathology grade > 1) between January 2012 and May 2022 who were negative for csPCa at baseline MRI. A DL model was developed using baseline MRI and clinical parameters (age, prostate-specific antigen [PSA] level, PSA density, and prostate volume) to predict the time to PCa progression (defined as csPCa diagnosis at follow-up).
View Article and Find Full Text PDFCells
December 2024
Karmanos Cancer Institute, Department of Oncology, School of Medicine, Wayne State University, 4100 John R Street, Detroit, MI 48201, USA.
The DNA replication machinery is highly conserved from bacteria to eukaryotic cells. Faithful DNA replication is vital for cells to transmit accurate genetic information to the next generation. However, both internal and external DNA damages threaten the intricate DNA replication process, leading to the activation of the DNA damage response (DDR) system.
View Article and Find Full Text PDFHealthcare (Basel)
December 2024
Interlevel Clinical Management Unit of Physical Medicine and Rehabilitation, Reina Sofía University Hospital, Córdoba and Guadalquivir Health District, 14011 Córdoba, Spain.
: Shoulder pain is a very common health issue among adults, being 8% due to calcifying tendinopathies (CT) of the shoulder. The evolutionary process of this lesion can be classified according to Bianchi Martinoli, depending on the ultrasound appearance. In 50% of cases, with first-line treatments, they resolve spontaneously.
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