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Knowledge and Current Practices in Monogenic Uveitis: An International Survey by IUSG and AIDA Network.
Ophthalmol Ther
January 2024
Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena and Azienda Ospedaliero-Universitaria Senese, (European Reference Network (ERN) for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases (RITA) Center), Policlinico "Le Scotte", Viale Bracci 16, 53100, Siena, Italy.
Article Synopsis
- The study investigates the awareness and diagnostic practices related to monogenic uveitis (mU) among uveitis specialists through an anonymous survey conducted with members of the Autoinflammatory Diseases Alliance and International Uveitis Study Group.
- Results showed that a majority of participants rated their knowledge of mU as poor, with 60.4% identifying NOD2 as the primary gene, and success rates in clinical scenarios varied significantly, especially among those in multidisciplinary teams.
- The findings highlight knowledge gaps and barriers in prescribing disease-modifying anti-rheumatic drugs (DMARDs), suggesting that the results could guide the development of better clinical guidelines and improve patient care.
Evaluating Measurement Properties of Patient-Reported Outcome Measures in Glaucoma: A Systematic Review.
Ophthalmol Glaucoma
November 2023
Department of Ophthalmology, Schulich School of Medicine, Western University, London, Ontario; Ivey Eye Institute, St. Joseph's Health Care, London, Ontario.
Topic: The purpose of the current study was to systematically identify and evaluate existing patient-reported outcome measures (PROMs) for clinical glaucoma practice.
Clinical Relevance: Understanding and incorporating patient preferences into decision-making is now recognized as critical for optimal resource allocation, especially in technologically advancing areas, such as minimally invasive surgeries. Patient-reported outcome measures are instruments designed to evaluate the health outcomes that are most important to patients.
The Problem of Vascularization of Precancerous Lesions of the Colon and Development of Hypoxia at the Incipient Stages of Blastomogenesis.
Bull Exp Biol Med
October 2022
Department of Morphological and Molecular Genetic Tumor Diagnostics, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation, Moscow, Russia.
The features of the blood supply in the colon mucosa during the development of hyperplastic and dysplastic processes, and early neoplastic lesions were studied. The study cohort comprised the material of 92 patients of the N. N.
View Article and Find Full Text PDFGonioscopy-assisted transluminal trabeculotomy in neovascular glaucoma: Salvaging the conventional outflow pathway.
Am J Ophthalmol Case Rep
December 2022
Department of Ophthalmology and Visual Science, University of Chicago Medical Center, Chicago, IL, USA.
Article Synopsis
- A case of acute neovascular glaucoma (NVG) caused by central retinal vein occlusion was treated using gonioscopy-assisted transluminal trabeculotomy (GATT) along with anti-VEGF injection and panretinal photocoagulation.
- After nine months, the patient maintained intraocular pressure (IOP) control without medication, but missed follow-up, leading to a recurrence of acute NVG and complete synechial closure, necessitating aqueous shunt implantation.
- This case highlights the potential effectiveness of angle surgery for restoring aqueous outflow in acute NVG, alongside continual anti-neovascular treatments until the disease stabilizes.
Regional Lymph Node Metastasis and Axillary Surgery of Microinvasive Breast Cancer: A Population-Based Study.
Diagnostics (Basel)
April 2022
Center of Oncology, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Microinvasive breast cancer (MBC for short) is a rare entity with the decision of axillary surgery under debate in clinical practice. We aimed to unravel the lymph node metastasis (LNM) rate, axillary surgery, and prognosis of MBC based on 11,692 patients derived from the Surveillance Epidemiology and End Results (SEER) database between 2003 and 2015. In this retrospective study, 19.
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